Ohmi T, Mue S, Takahashi M, Ishihara M, Tamura G, Takishima T
Ann Allergy. 1982 Jan;48(1):40-3.
The concomitant injection of isoproterenol with house dust allergen inhibited the immediate skin allergic reaction in asthmatic patients. Pretreatment with dibutyryl cyclic AMP showed an inhibitory effect on the whealing formation to the allergen. Those results showed the inhibitory effect of isoproterenol on the skin reaction through increasing intracellular cyclic AMP levels.
异丙肾上腺素与屋尘过敏原同时注射可抑制哮喘患者的速发型皮肤过敏反应。用二丁酰环磷腺苷预处理对过敏原引起的风团形成有抑制作用。这些结果表明异丙肾上腺素通过提高细胞内环磷腺苷水平对皮肤反应有抑制作用。
