Dupré A, Christol B, Lassère J
Ann Dermatol Venereol. 1981;108(11):829-34.
Subjects afflicted with atopic dermatitis are particularly predisposed to such viral superinfections as verruca, herpes (eczema herpeticum) and vaccinia (eczema vaccinatum). Knowledge of superinfection by the molluscum contagiosum virus is more recent and the authors describe one case. The orf virus (responsible for ovine ecthyma contagiosum), however, has never been described as responsible for the profuse superinfection of an atopic eczema. The authors observed one case of this in a child, atypical as result of his age (16 months), the cervical localization and the aspect, which was a telangiectasic granuloma type of the initial element, and finally of the satellization observed one week later. This child suffered from a generalized atopic eczema. Propagation of the orf lesions could have been favored by scratching, local corticoid treatment and by the deficit in cellular immunity observed in patient with atopic dermatitis. Indeed, viral superinfections, which are unusual by their profusion or their chronic nature, are often observed in immunodepressed subjects.
患有特应性皮炎的患者特别容易发生病毒重叠感染，如疣、疱疹（疱疹样湿疹）和牛痘（种痘性湿疹）。传染性软疣病毒重叠感染的相关知识出现得较晚，本文作者描述了1例病例。然而，羊痘疮病毒（引起羊传染性脓疱）从未被描述为导致特应性湿疹大量重叠感染的病因。作者观察到1例发生在儿童身上的此类病例，由于其年龄（16个月）、颈部病损部位、初始病损表现为毛细血管扩张性肉芽肿类型，以及1周后观察到的卫星状病损，该病例具有非典型性。这名儿童患有全身性特应性皮炎。搔抓、局部皮质类固醇治疗以及特应性皮炎患者中观察到的细胞免疫缺陷可能有利于羊痘疮病损的扩散。事实上，病毒重叠感染因其大量发生或慢性病程而不常见，常出现在免疫抑制的患者中。
