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锂对正常及慢性粒细胞白血病集落形成细胞（CFU-GM）的影响。

Effect of lithium on normal and chronic granulocytic leukemia colony forming cells (CFU-GM).

作者信息

Aglietta M, Leone A, Piacibello W

出版信息

Experientia. 1981 Dec 15;37(12):1340-1. doi: 10.1007/BF01948399.

DOI:10.1007/BF01948399
PMID:6276221
Abstract

The effect of lithium on normal and chronic granulocytic leukemia (CGL) granulo-monocytic precursors (CFU-GM) has been studied. Lithium slightly increases normal CFU-GM growth whereas it is without effect or moderately inhibitory for CGL CFU-GM. It is suggested that it is unlikely that lithium therapy enhances the proliferation of a silent leukemic clone.

摘要

锂对正常及慢性粒细胞白血病（CGL）粒-单核细胞前体细胞（CFU-GM）的作用已得到研究。锂能轻微增加正常CFU-GM的生长，而对CGL CFU-GM则无作用或有中度抑制作用。提示锂治疗不太可能增强隐匿性白血病克隆的增殖。

相似文献

1
Effect of lithium on normal and chronic granulocytic leukemia colony forming cells (CFU-GM).锂对正常及慢性粒细胞白血病集落形成细胞（CFU-GM）的影响。
Experientia. 1981 Dec 15;37(12):1340-1. doi: 10.1007/BF01948399.
2
The effect of lithium chloride on granulocyte-macrophage progenitor cells (CFU-GM) and clonogenic leukaemic blasts (CFU-L) in the cultures in vitro.
Arch Immunol Ther Exp (Warsz). 1991;39(5-6):495-500.
3
Failure of bone marrow cryopreservation in chronic granulocytic leukemia: relation to excessive granulo-macrophagic progenitor pool.慢性粒细胞白血病中骨髓冷冻保存失败：与过度的粒-巨噬祖细胞池的关系。
Int J Cell Cloning. 1986 Jul;4(4):250-62. doi: 10.1002/stem.5530040403.
4
The sensitivity to hyperthermia of human granulocyte/macrophage progenitor cells (CFU-GM) derived from blood or marrow of normal subjects and patients with chronic granulocytic leukaemia.源自正常受试者以及慢性粒细胞白血病患者的血液或骨髓的人粒细胞/巨噬细胞祖细胞（CFU-GM）对热疗的敏感性。
Br J Cancer. 1984 Dec;50(6):745-51. doi: 10.1038/bjc.1984.251.
5
Effect of interleukin-1, GM-CSF, erythropoietin, and lithium on the toxicity associated with 3'-azido-3'-deoxythymidine (AZT) in vitro on hematopoietic progenitors (CFU-GM, CFU-MEG, and BFU-E) using murine retrovirus-infected hematopoietic cells.利用鼠逆转录病毒感染的造血细胞，研究白细胞介素-1、粒细胞巨噬细胞集落刺激因子、促红细胞生成素和锂对3'-叠氮-3'-脱氧胸苷（AZT）体外对造血祖细胞（CFU-GM、CFU-MEG和BFU-E）毒性的影响。
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Effects of recombinant human tumor necrosis factor on highly enriched hematopoietic progenitor cell populations from normal human bone marrow and peripheral blood and bone marrow from patients with chronic myeloid leukemia.重组人肿瘤坏死因子对来自正常人骨髓、外周血以及慢性髓性白血病患者骨髓的高度富集造血祖细胞群体的影响。
Cancer Res. 1987 Sep 15;47(18):4788-94.
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Expression of myeloid differentiation antigens on normal and chronic granulocytic leukemia erythroid progenitor cells identified by monoclonal antibodies.用单克隆抗体鉴定正常及慢性粒细胞白血病红系祖细胞上髓系分化抗原的表达。
Arch Immunol Ther Exp (Warsz). 1987;35(4):519-29.
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Lithium stimulation of murine hematopoiesis in liquid culture: an effect mediated by marrow stromal cells.锂对液体培养中小鼠造血作用的刺激：一种由骨髓基质细胞介导的效应。
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Purification of an in vitro inhibitor of normal myelopoiesis using a monoclonal antibody directed to a common antigen of myelogenous leukemia (CAMAL).使用针对髓性白血病共同抗原（CAMAL）的单克隆抗体纯化正常骨髓生成的体外抑制剂。
Exp Hematol. 1991 Feb;19(2):136-42.
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Preferential inhibition by cytarabine of CFU-GM from patients with chronic granulocytic leukemia.阿糖胞苷对慢性粒细胞白血病患者CFU - GM的优先抑制作用。
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本文引用的文献

1
More on lithium and leukemia.更多关于锂与白血病的内容。
N Engl J Med. 1980 Jul 31;303(5):283.
2
The effect of lithium on murine hematopoiesis in a liquid culture system.锂对液体培养系统中小鼠造血作用的影响。
N Engl J Med. 1980 Mar 27;302(13):713-9. doi: 10.1056/NEJM198003273021303.
3
Insensitivity of chronic myeloid leukemia cells to inhibition of growth by prostaglandin E1.慢性髓性白血病细胞对前列腺素E1抑制生长作用的不敏感性。
Cancer Res. 1980 Jul;40(7):2507-11.
4
Lithium and acute monocytic leukemia.锂与急性单核细胞白血病
N Engl J Med. 1980 Apr 3;302(14):808. doi: 10.1056/NEJM198004033021413.
5
Chronic myeloid leukemia and lithium.慢性粒细胞白血病与锂
Ann Intern Med. 1980 Feb;92(2 Pt 1):262. doi: 10.7326/0003-4819-92-2-262_2.
6
Detection of basophils growing in semisolid agar culture.检测在半固体琼脂培养中生长的嗜碱性粒细胞。
Exp Hematol. 1981 Feb;9(2):95-100.
7
Human bone marrow colony growth in agar-gel.人骨髓在琼脂凝胶中的集落生长。
J Cell Physiol. 1970 Aug;76(1):77-84. doi: 10.1002/jcp.1040760111.
8
Evidence that lithium induces human granulocyte proliferation: elevated serum vitamin B 12 binding capacity in vivo and granulocyte colony proliferation in vitro.锂诱导人类粒细胞增殖的证据：体内血清维生素B12结合能力升高及体外粒细胞集落增殖。
Br J Haematol. 1973 Jun;24(6):767-71. doi: 10.1111/j.1365-2141.1973.tb01704.x.
9
Studies on the haematologic and cytogenetic effect of lithium.
Acta Med Scand. 1975 Oct;198(4):281-6. doi: 10.1111/j.0954-6820.1975.tb19541.x.
10
Lithium-induced granulocytosis.锂诱导的粒细胞增多症。
Ann Intern Med. 1978 Jun;88(6):809-10. doi: 10.7326/0003-4819-88-6-809_2.