锂对正常及慢性粒细胞白血病集落形成细胞（CFU-GM）的影响。
Effect of lithium on normal and chronic granulocytic leukemia colony forming cells (CFU-GM).
作者信息
Aglietta M, Leone A, Piacibello W
出版信息
Experientia. 1981 Dec 15;37(12):1340-1. doi: 10.1007/BF01948399.
PMID:6276221
Abstract
The effect of lithium on normal and chronic granulocytic leukemia (CGL) granulo-monocytic precursors (CFU-GM) has been studied. Lithium slightly increases normal CFU-GM growth whereas it is without effect or moderately inhibitory for CGL CFU-GM. It is suggested that it is unlikely that lithium therapy enhances the proliferation of a silent leukemic clone.
摘要
锂对正常及慢性粒细胞白血病（CGL）粒-单核细胞前体细胞（CFU-GM）的作用已得到研究。锂能轻微增加正常CFU-GM的生长，而对CGL CFU-GM则无作用或有中度抑制作用。提示锂治疗不太可能增强隐匿性白血病克隆的增殖。
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