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感染牛血浆中的一种非免疫球蛋白蛋白可阻断牛白血病病毒基因组的表达。

Expression of bovine leukemia virus genome is blocked by a nonimmunoglobulin protein in plasma from infected cattle.

作者信息

Gupta P, Ferrer J F

出版信息

Science. 1982 Jan 22;215(4531):405-7. doi: 10.1126/science.6276975.

DOI:10.1126/science.6276975
PMID:6276975
Abstract

Plasma of cattle infected with bovine leukemia virus contains a soluble factor that blocks the expression of the viral genome in cultured lymphocytes. The blocking factor is not present in plasma of bovine leukemia virus-free cattle or of cattle infected with common bovine viruses. Blocking of bovine leukemia virus expression by the plasma factor is reversible, and seems to be mediated by a nonimmunoglobulin protein molecule.

摘要

感染牛白血病病毒的牛血浆中含有一种可溶性因子，该因子可阻断病毒基因组在培养淋巴细胞中的表达。无牛白血病病毒的牛或感染常见牛病毒的牛血浆中不存在这种阻断因子。血浆因子对牛白血病病毒表达的阻断是可逆的，且似乎由一种非免疫球蛋白蛋白质分子介导。

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