Cassel D M, Young S W, Brody W R, Muller H H, Hall A L
J Comput Assist Tomogr. 1982 Feb;6(1):141-6. doi: 10.1097/00004728-198202000-00023.
An emulsion of Ethiodol and Pluronic was evaluated as a vascular (blood pool) imaging agent with both the GE experimental scanned projection radiography system and conventional computed tomography (CT), 475 mg iodine/kg body weight of emulsion, was injected into 11 rabbits with thigh muscle V2 carcinomas. Both projection radiography scans and CT scans visualized aorta, vena cava, pulmonary, and femoral vessels, and distorted vessels around tumors for 20 min after infusion. This persistent vascular visualization allowed CT scanning at multiple contiguous levels, which could be followed by reformatting in the sagittal and coronal planes. Following diatrizoate in identical iodine/kg doses, vascular visualization persisted for only 1 min after infusion. Blood pool agents are ideal for projection radiography systems and CT reformatting of vascular anatomy.
对碘油和普朗尼克的乳剂作为血管(血池)显像剂进行了评估,使用了通用电气实验性扫描投影射线照相系统和传统计算机断层扫描(CT)。将每千克体重含475毫克碘的乳剂注入11只患有大腿肌肉V2癌的兔子体内。在注入后20分钟内,投影射线照相扫描和CT扫描均显示出主动脉、腔静脉、肺血管和股血管以及肿瘤周围扭曲的血管。这种持续的血管显影使得能够在多个连续层面进行CT扫描,随后还可以在矢状面和冠状面进行重新格式化。在注入相同碘/千克剂量的泛影葡胺后,血管显影在注入后仅持续1分钟。血池显像剂是投影射线照相系统和血管解剖结构CT重新格式化的理想选择。