A quantitative analysis of the Na+-dependence of Vmax of the fast action potential in mammalian ventricular myocardium. Saturation characteristics and the modulation of a drug-induced INa blockade by [Na+]o.

Suppr

超能文献

作者信息

Kohlhardt M

出版信息

Pflugers Arch. 1982 Feb;392(4):379-87. doi: 10.1007/BF00581635.

DOI:10.1007/BF00581635

PMID:6280128

Abstract

摘要

相似文献

A quantitative analysis of the Na+-dependence of Vmax of the fast action potential in mammalian ventricular myocardium. Saturation characteristics and the modulation of a drug-induced INa blockade by [Na+]o.

Pflugers Arch. 1982 Feb;392(4):379-87. doi: 10.1007/BF00581635.

Tonic and phasic INa blockade by antiarrhythmics. Different properties of drug binding to fast sodium channels as judged from Vmax studies with propafenone and derivatives in mammalian ventricular myocardium.抗心律失常药物对钠电流的强直和阵发阻滞作用。从普罗帕酮及其衍生物在哺乳动物心室肌中的最大反应速度研究判断药物与快速钠通道结合的不同特性。

Pflugers Arch. 1983 Mar 1;396(3):199-209. doi: 10.1007/BF00587856.

Block of sodium currents by antiarrhythmic agents: analysis of the electrophysiologic effects of propafenone in heart muscle.

Am J Cardiol. 1984 Nov 14;54(9):13D-19D. doi: 10.1016/s0002-9149(84)80279-9.

Properties of Vmax block of INa-mediated action potentials during combined application of antiarrhythmic drugs in cardiac muscle.抗心律失常药物联合应用时心肌中 INa 介导的动作电位 Vmax 阻滞的特性。

Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):235-44. doi: 10.1007/BF00572439.

Inhibition of Vmax of the action potential by propafenone and its voltage-, time- and pH-dependence in mammalian ventricular myocardium.普罗帕酮对哺乳动物心室肌动作电位Vmax的抑制作用及其电压、时间和pH依赖性

Naunyn Schmiedebergs Arch Pharmacol. 1980;315(1):55-62. doi: 10.1007/BF00504230.

Effects of etafenone and antiarrhythmic drugs on Na and Ca channels of guinea pig atrial muscle.乙胺碘呋酮和抗心律失常药物对豚鼠心房肌钠通道和钙通道的作用。

J Cardiovasc Pharmacol. 1979 Sep-Oct;1(5):561-70. doi: 10.1097/00005344-197909000-00008.

Electrophysiological evidence that local anesthetics and antiarrhythmic drugs bind to a specific receptor site in cardiac sodium channels: displacement of bupivacaine by lidocaine.局部麻醉药和抗心律失常药物与心脏钠通道中的特定受体位点结合的电生理证据：利多卡因对布比卡因的置换

Proc West Pharmacol Soc. 1984;27:23-5.

Negative inotropic effects of tetrodotoxin and seven class 1 antiarrhythmic drugs in relation to sodium channel blockade.河豚毒素和七种Ⅰ类抗心律失常药物的负性肌力作用与钠通道阻滞的关系。

Naunyn Schmiedebergs Arch Pharmacol. 1986 Feb;332(2):184-95. doi: 10.1007/BF00511411.

Electrophysiological effects of propafenone on isolated guinea-pig ventricular muscle and sheep Purkinje fibres.普罗帕酮对离体豚鼠心室肌和绵羊浦肯野纤维的电生理作用。

Eur J Pharmacol. 1985 Dec 3;118(3):331-40. doi: 10.1016/0014-2999(85)90144-x.

Electrophysiological effects of propafenone in untreated and propafenone-pretreated guinea-pig atrial and ventricular muscle fibres.普罗帕酮对未经处理及经普罗帕酮预处理的豚鼠心房和心室肌纤维的电生理效应。

Br J Pharmacol. 1985 Dec;86(4):765-75. doi: 10.1111/j.1476-5381.1985.tb11098.x.

引用本文的文献

A Literature Review of the Use of Sodium Bicarbonate for the Treatment of QRS Widening.碳酸氢钠用于治疗QRS波增宽的文献综述

J Med Toxicol. 2016 Mar;12(1):121-9. doi: 10.1007/s13181-015-0483-y.

Saturation characteristics, Ca2+ ions and drug-induced block of cardiac Isi-mediated action potentials.饱和特性、钙离子与药物诱导的心脏内向整流钾电流（Isi）介导的动作电位阻滞

Naunyn Schmiedebergs Arch Pharmacol. 1983 Jul;323(3):251-60. doi: 10.1007/BF00497671.

Pflugers Arch. 1983 Mar 1;396(3):199-209. doi: 10.1007/BF00587856.

Saturation of calcium channels and surface charge effects in skeletal muscle fibres of the frog.青蛙骨骼肌纤维中钙通道的饱和度及表面电荷效应

J Physiol. 1984 Jun;351:135-54. doi: 10.1113/jphysiol.1984.sp015238.

Br J Pharmacol. 1985 Dec;86(4):765-75. doi: 10.1111/j.1476-5381.1985.tb11098.x.

Modelling frequency- and voltage-dependent effects of a class I antiarrhythmic drug (nicainoprol) on Vmax of the cardiac action potential from guinea-pig papillary muscle.

Naunyn Schmiedebergs Arch Pharmacol. 1989 Oct;340(4):456-64. doi: 10.1007/BF00167049.

On the relationship between V max of slow responses and Ca-current availability in whole-cell clamped guinea pig heart cells.

Pflugers Arch. 1987 Sep;410(1-2):15-22. doi: 10.1007/BF00581890.

Naunyn Schmiedebergs Arch Pharmacol. 1985 Sep;330(3):235-44. doi: 10.1007/BF00572439.

Use-dependent effects of pirmenol on Vmax and conduction in guinea-pig ventricular myocardium.吡美诺对豚鼠心室肌最大反应速率和传导的使用依赖性效应。

Br J Pharmacol. 1990 Apr;99(4):815-9. doi: 10.1111/j.1476-5381.1990.tb13012.x.

Blockade of cardiac sodium channels. Competition between the permeant ion and antiarrhythmic drugs.心脏钠通道的阻断。通透离子与抗心律失常药物之间的竞争。

J Clin Invest. 1992 Aug;90(2):368-81. doi: 10.1172/JCI115871.

本文引用的文献

The sodium-potassium hypothesis as the basis of electrical activity in frog ventricle.钠钾假说作为蛙心室电活动的基础。

J Physiol. 1960 Dec;154(2):385-407. doi: 10.1113/jphysiol.1960.sp006586.

Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo.钠和钾离子通过枪乌贼巨大轴突膜所携带的电流。

J Physiol. 1952 Apr;116(4):449-72. doi: 10.1113/jphysiol.1952.sp004717.

Cardiac resting and action potentials recorded with an intracellular electrode.用细胞内电极记录的心脏静息电位和动作电位。

J Physiol. 1951 Sep;115(1):74-94. doi: 10.1113/jphysiol.1951.sp004653.

The effect of the cardiac membrane potential on the rapid availability of the sodium-carrying system.心脏膜电位对钠转运系统快速可用性的影响。

J Physiol. 1955 Jan 28;127(1):213-24. doi: 10.1113/jphysiol.1955.sp005250.

INFLUENCE OF LITHIUM IONS ON THE TRANSMEMBRANE POTENTIAL AND CATION CONTENT OF CARDIAC CELLS.锂离子对心肌细胞跨膜电位及阳离子含量的影响

J Gen Physiol. 1964 Jan;47(3):501-30. doi: 10.1085/jgp.47.3.501.

Action potential of amphibian single auricular muscle fiber: a dual response.两栖类单耳肌纤维的动作电位：双重反应。

Am J Physiol. 1961 Dec;201:1101-8. doi: 10.1152/ajplegacy.1961.201.6.1101.

Perfusion of a strip of mammalian ventricle; effects of K-rich and Na-deficient solutions on transmembrane potentials.

Circ Res. 1959 May;7(3):461-5. doi: 10.1161/01.res.7.3.461.

Effects of calcium ions and local anesthetics on electrical properties of Purkinje fibres.钙离子和局部麻醉药对浦肯野纤维电特性的影响。

J Physiol. 1955 Sep 28;129(3):568-82. doi: 10.1113/jphysiol.1955.sp005379.

Sodium current in single rat heart muscle cells.单个大鼠心肌细胞中的钠电流。

J Physiol. 1981 Sep;318:479-500. doi: 10.1113/jphysiol.1981.sp013879.

Influence of intercellular clefts on potential and current distribution in a multifiber preparation.细胞间裂对多纤维制剂中电位和电流分布的影响。

Biophys J. 1980 May;30(2):327-49. doi: 10.1016/S0006-3495(80)85098-3.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验