Blackwelder W C, Dolin R, Mittal K K, McNamara P M, Payne F J
Am J Epidemiol. 1982 Apr;115(4):569-76. doi: 10.1093/oxfordjournals.aje.a113338.
In a population-based study of herpesvirus infection and human leukocyte antigen (HLA) phenotype, conducted during the period 1977-1979 in the Framingham Study cohort, HLA-Bw16 was found less often and HLA-Cw2 more often in individuals with histories of herpes labialis than in other individuals. Similarly, both geometric mean antibody titer to herpes simplex type 1 and proportion of individuals with detectable antibody were higher in those without Bw16 and in those with Cw2. No strong association was found between HLA and history of herpes zoster or titer to herpes simplex type 2, varicella-zoster virus or cytomegalovirus.
在1977年至1979年期间对弗雷明汉研究队列进行的一项基于人群的疱疹病毒感染与人类白细胞抗原（HLA）表型的研究中，发现有唇疱疹病史的个体中，HLA - Bw16出现的频率较低，而HLA - Cw2出现的频率较高。同样，在没有Bw16的个体和有Cw2的个体中，单纯疱疹病毒1型的几何平均抗体滴度以及可检测到抗体的个体比例都更高。未发现HLA与带状疱疹病史或单纯疱疹病毒2型、水痘 - 带状疱疹病毒或巨细胞病毒的滴度之间存在强关联。
