Sessions R B, Lehane D E, Smith R J, Bryan R N, Suen J Y
Arch Otolaryngol. 1982 Apr;108(4):221-4. doi: 10.1001/archotol.1982.00790520021007.
Adenoid cystic carcinoma (ACC) is unique among salivary gland tumors in both its natural history and in its response to nonsurgical treatment methods (ie, radiation and chemotherapy). The chemotherapeutic agent, cisplatin, seems to be unique in its ability to affect ACC. It might be that ACCs of the minor salivary glands are especially vulnerable to the intra-arterial method of administering this drug, because there are accessible feeding vessels to most locations in which these tumors occur. We have treated four patients with advanced ACC with intra-arterial cisplatin. The responses suggest that this method may be a useful adjunct in the management of this tumor both as a preoperative and as a palliative measure.
腺样囊性癌（ACC）在唾液腺肿瘤中无论其自然病程还是对非手术治疗方法（即放疗和化疗）的反应都很独特。化疗药物顺铂在影响ACC方面似乎具有独特性。可能是小唾液腺的ACC对这种药物的动脉内给药方法特别敏感，因为这些肿瘤发生的大多数部位都有可及的供血血管。我们用动脉内注射顺铂治疗了4例晚期ACC患者。这些反应表明，这种方法作为术前和姑息性措施，可能是管理这种肿瘤的一种有用辅助手段。
