Togashi T, Kuwajima S, Takebayashi T, Nakamura S
Hokkaido Igaku Zasshi. 1982 Jan;57(1):101-3.
Serum specimens drawn at random from Hokkaido inhabitants were tested for antibody to the hepatitis A virus (anti-HAV) by radioimmunoassay. The prevalence in different age groups was as follows, cord blood and newborn infants 44.4%, under one year 0%, 1-9 years 5.3%, 10-19 years 0%, 20-29 years 9.1%, 30-39 years 80%, 40-49 years 90%, and over 50 years 100%. This survey confirmed that antibody against HAV could pass through placenta and HAV had been very common virus by the 1950's in Hokkaido.
从北海道居民中随机抽取血清样本,采用放射免疫分析法检测甲型肝炎病毒抗体(抗-HAV)。不同年龄组的患病率如下:脐带血和新生儿为44.4%,1岁以下为0%,1-9岁为5.3%,10-19岁为0%,20-29岁为9.1%,30-39岁为80%,40-49岁为90%,50岁以上为100%。这项调查证实,抗-HAV抗体可以通过胎盘传递,并且到20世纪50年代,甲型肝炎病毒在北海道已经是一种非常常见的病毒。