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[高血压患者外周血肾素 - 血管紧张素系统指标及肾脏激肽释放酶 - 激肽系统]

[Peripheral blood renin-angiotensin system indices and the kallikrein-kinin system of the kidneys in hypertension].

作者信息

Almazov V A, Sokolova L A, Sukovatova N M

出版信息

Kardiologiia. 1982 Mar;22(3):25-9.

PMID:6281512
Abstract

In III patients with hypertension the activity of renin in blood plasma and excretion of kallikrein and kinins in urine and in 53 the activity of carboxycatepsin were determined. Hypertensive patients showed enhanced renin activity and excretion of kallikrein and kinins with urine. A more significant rise of these figures is noted during the early stage of illness, with labile arterial hypertension. In stable hypertension renin activity is lower than in the labile form, however this index remained higher than in the control group. Activity of kallikrein-kinin system and of carboxykatepsin in stable hypertension drops below normal.

摘要

对3例高血压患者测定了血浆肾素活性、尿中激肽释放酶和激肽的排泄量,并对53例患者测定了羧肽酶活性。高血压患者表现出肾素活性增强以及尿中激肽释放酶和激肽排泄量增加。在疾病早期,即不稳定型动脉高血压阶段,这些指标的升高更为显著。在稳定型高血压中,肾素活性低于不稳定型,但该指标仍高于对照组。稳定型高血压中激肽释放酶-激肽系统和羧肽酶的活性低于正常水平。

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