原发性肝细胞癌中的黄曲霉毒素B1、B2、G1、G2
Aflatoxins, B1, B2, G1, G2 in primary liver cell carcinoma.
作者信息
Onyemelukwe G C, Ogbadu G H, Salifu A
出版信息
Toxicol Lett. 1982 Feb;10(2-3):309-12. doi: 10.1016/0378-4274(82)90093-5.
Aflatoxin B1, B2, G1, G2 levels were determined in sera of 20 patients with primary liver cell carcinoma (CC). Values of B1 above 0.15 microgram/ml were obtained in sera of three patients. Hepatitis B surface antigen (HBsAg) was detected in only 35% of patients. 50-90% of serum levels were cleared in 24 h in three patients studied. Although it is inconclusive as to the carcinogenic potential of aflatoxins in adult man, foodstuffs should be protected from excessive aflatoxin contamination.
测定了20例原发性肝细胞癌（CC）患者血清中黄曲霉毒素B1、B2、G1、G2的水平。三名患者血清中B1值高于0.15微克/毫升。仅35%的患者检测到乙肝表面抗原（HBsAg）。在三名接受研究的患者中，50 - 90%的血清水平在24小时内清除。尽管黄曲霉毒素对成年男性的致癌潜力尚无定论，但食品应防止受到过量黄曲霉毒素污染。
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