聚（腺苷二磷酸核糖）聚合酶抑制剂可刺激正常人淋巴细胞中进行非预定的脱氧核糖核酸合成。 - Suppr

Suppr

超能文献

Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled deoxyribonucleic acid synthesis in normal human lymphocytes.

作者信息

Sims J L, Sikorski G W, Catino D M, Berger S J, Berger N A

出版信息

Biochemistry. 1982 Apr 13;21(8):1813-21. doi: 10.1021/bi00537a017.

DOI:10.1021/bi00537a017

PMID:6282320

Abstract

摘要

相似文献

Poly(adenosinediphosphoribose) polymerase inhibitors stimulate unscheduled deoxyribonucleic acid synthesis in normal human lymphocytes.聚（腺苷二磷酸核糖）聚合酶抑制剂可刺激正常人淋巴细胞中进行非预定的脱氧核糖核酸合成。

Biochemistry. 1982 Apr 13;21(8):1813-21. doi: 10.1021/bi00537a017.

Poly(ADP-ribose) Polymerase inhibitors preserve nicotinamide adenine dinucleotide and adenosine 5'-triphosphate pools in DNA-damaged cells: mechanism of stimulation of unscheduled DNA synthesis.聚（ADP-核糖）聚合酶抑制剂可维持DNA损伤细胞中的烟酰胺腺嘌呤二核苷酸和三磷酸腺苷水平：刺激非预定DNA合成的机制

Biochemistry. 1983 Oct 25;22(22):5188-94. doi: 10.1021/bi00291a019.

Inhibitors of poly(ADP-ribose) polymerase enhance unscheduled DNA synthesis in human peripheral lymphocytes.聚（ADP - 核糖）聚合酶抑制剂可增强人外周血淋巴细胞中的非预定DNA合成。

Biochem Biophys Res Commun. 1981 May 15;100(1):463-70. doi: 10.1016/s0006-291x(81)80119-2.

Poly(ADP-ribose) synthetase inhibitors enhance streptozotocin-induced killing of insulinoma cells by inhibiting the repair of DNA strand breaks.

FEBS Lett. 1982 Aug 23;145(2):298-302. doi: 10.1016/0014-5793(82)80187-7.

Effects of nicotinamide on NAD and poly(ADP-ribose) metabolism in DNA-damaged human lymphocytes.烟酰胺对DNA损伤的人淋巴细胞中NAD及聚（ADP - 核糖）代谢的影响

J Supramol Struct Cell Biochem. 1981;16(3):281-8. doi: 10.1002/jsscb.1981.380160308.

Exp Cell Res. 1985 Mar;157(1):271-5. doi: 10.1016/0014-4827(85)90169-7.

Poly(ADP-ribose) polymerase mediates the suicide response to massive DNA damage: studies in normal and DNA-repair defective cells.聚（ADP-核糖）聚合酶介导对大量DNA损伤的自杀反应：对正常细胞和DNA修复缺陷细胞的研究。

Princess Takamatsu Symp. 1983;13:219-26.

Quantitative studies of inhibitors of ADP-ribosylation in vitro and in vivo.ADP-核糖基化抑制剂的体外和体内定量研究。

J Biol Chem. 1989 Mar 15;264(8):4312-7.

Potentiation of cell killing by inhibitors of poly(ADP-ribose) polymerase in four rodent cell lines exposed to N-methyl-N-nitrosourea or UV light.聚（ADP-核糖）聚合酶抑制剂对暴露于N-甲基-N-亚硝基脲或紫外线的四种啮齿动物细胞系细胞杀伤作用的增强。

Chem Biol Interact. 1982 Feb;38(3):325-38. doi: 10.1016/0009-2797(82)90062-x.

[DNA repair processes in thymus and spleen cells of rats in vitro as affected by the poly(ADP-ribose) polymerase inhibitor 3-aminobenzamide].[聚（ADP - 核糖）聚合酶抑制剂3 - 氨基苯甲酰胺对大鼠胸腺和脾细胞体外DNA修复过程的影响]

Zentralbl Veterinarmed A. 1985 Feb;32(2):123-34.

引用本文的文献

Niacin analogue, 6-Aminonicotinamide, a novel inhibitor of hepatitis B virus replication and HBsAg production.烟酰胺类似物，6-氨基烟酰胺，一种新型乙型肝炎病毒复制和 HBsAg 产生的抑制剂。

EBioMedicine. 2019 Nov;49:232-246. doi: 10.1016/j.ebiom.2019.10.022. Epub 2019 Oct 31.

Detection and quantification of poly-ADP-ribosylated cellular proteins of spleen and liver tissues of mice in vivo by slot and Western blot immunoprobing using polyclonal antibody against mouse ADP-ribose polymer.利用抗小鼠 ADP 核糖聚合物的多克隆抗体，通过狭缝印迹和 Western 印迹免疫检测法在体内检测和定量小鼠脾脏和肝脏组织中多聚 ADP 核糖基化的细胞蛋白。

Mol Cell Biochem. 2005 Oct;278(1-2):213-21. doi: 10.1007/s11010-005-7588-6.

DNA repair dependent NAD+ metabolism is impaired in cells from patients with Fanconi's anemia.范可尼贫血患者细胞中依赖DNA修复的NAD+代谢受损。

EMBO J. 1983;2(3):303-7. doi: 10.1002/j.1460-2075.1983.tb01423.x.

In vitro enhancement of antitumor activity of a water-soluble duocarmycin derivative, KW-2189, by caffeine-mediated DNA-repair inhibition in human lung cancer cells.咖啡因介导的DNA修复抑制增强水溶性多卡霉素衍生物KW-2189对人肺癌细胞的体外抗肿瘤活性

Jpn J Cancer Res. 1997 Nov;88(11):1033-7. doi: 10.1111/j.1349-7006.1997.tb00326.x.

Crocidolite asbestos induces apoptosis of pleural mesothelial cells: role of reactive oxygen species and poly(ADP-ribosyl) polymerase.青石棉诱导胸膜间皮细胞凋亡：活性氧和聚（ADP - 核糖）聚合酶的作用

Environ Health Perspect. 1997 Sep;105 Suppl 5(Suppl 5):1147-52. doi: 10.1289/ehp.97105s51147.

Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen species.石棉通过活性氧诱导人和兔胸膜间皮细胞凋亡。

J Clin Invest. 1996 Nov 1;98(9):2050-9. doi: 10.1172/JCI119010.

Lesch-Nyhan syndrome and its pathogenesis: normal nicotinamide-adenine dinucleotide but reduced ATP concentrations that correlate with reduced poly(ADP-ribose) synthetase activity in HPRT-deficient lymphoblasts.莱施-奈恩综合征及其发病机制：烟酰胺腺嘌呤二核苷酸正常，但三磷酸腺苷浓度降低，这与次黄嘌呤-鸟嘌呤磷酸核糖转移酶缺陷的淋巴母细胞中聚（ADP-核糖）合成酶活性降低相关。

J Inherit Metab Dis. 1995;18(6):737-47. doi: 10.1007/BF02436765.

Growth-phase-dependent response to DNA damage in poly(ADP-ribose) polymerase deficient cell lines: basis for a new hypothesis describing the role of poly(ADP-ribose) polymerase in DNA replication and repair.聚（ADP - 核糖）聚合酶缺陷细胞系中DNA损伤的生长阶段依赖性反应：描述聚（ADP - 核糖）聚合酶在DNA复制和修复中作用的新假说基础

Mol Cell Biochem. 1994 Sep;138(1-2):61-9. doi: 10.1007/BF00928444.

Inhibitors and activators of ADP-ribosylation reactions.ADP核糖基化反应的抑制剂和激活剂。

Mol Cell Biochem. 1994 Sep;138(1-2):185-97. doi: 10.1007/BF00928461.

The immunosuppressive substance 2-chloro-2-deoxyadenosine modulates lipoprotein metabolism in a murine macrophage cell line (P388 cells).免疫抑制物质2-氯-2-脱氧腺苷可调节小鼠巨噬细胞系（P388细胞）中的脂蛋白代谢。

Lipids. 1994 Sep;29(9):627-33. doi: 10.1007/BF02536097.

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