四种具有不同特异性的用于中和1型脊髓灰质炎病毒的单克隆抗体。
Monoclonal antibodies of four different specificities for neutralization of type 1 polioviruses.
作者信息
Humphrey D D, Kew O M, Feorino P M
出版信息
Infect Immun. 1982 May;36(2):841-3. doi: 10.1128/iai.36.2.841-843.1982.
Abstract
Four independent hybridoma clones have been established that produce neutralizing antibodies specific to type 1 poliovirus. Each clone produced antibody which neutralized a distinct set of type 1 test strains: (i) all 15 strains tested; (ii) the inducer strain only; (iii) predominantly wild strains; or (iv) all vaccine-related and some wild strains.
摘要
已经建立了四个独立的杂交瘤克隆，它们产生针对1型脊髓灰质炎病毒的中和抗体。每个克隆产生的抗体能中和一组不同的1型测试毒株：（i）所有15株测试毒株；（ii）仅诱导株；（iii）主要是野生毒株；或（iv）所有与疫苗相关的毒株和一些野生毒株。
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