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有髓施万细胞内质网微丝异常增殖:两例超微结构研究

Abnormal proliferation of intraergastoplasmic microfilaments in myelinated schwann cells: ultrastructural study of two cases.

作者信息

Vallat J M, Vital C, LeBoutet M J, Loubet A, Brechenmacher C

出版信息

J Neuropathol Exp Neurol. 1982 Jul;41(4):460-5. doi: 10.1097/00005072-198207000-00008.

DOI:10.1097/00005072-198207000-00008
PMID:6283038
Abstract

We report the ultrastructural findings in superficial peroneal nerve biopsies in two patients, one with idiopathic sensory neuropathy and the other with the Guillain-Barré syndrome and Hodgkin's disease. In addition to demyelination, there was an intense proliferation of microfilaments within numerous vesicles of the endoplasmic reticulum of a great number of myelinated Schwann cells. This abnormality does not appear to have been previously reported in the literature. The mechanisms responsible for this finding are unknown.

摘要

我们报告了两名患者腓浅神经活检的超微结构结果,其中一名患有特发性感觉神经病,另一名患有格林-巴利综合征和霍奇金病。除脱髓鞘外,大量有髓施万细胞内质网的众多小泡内微丝强烈增生。这种异常此前似乎未见文献报道。导致这一发现的机制尚不清楚。

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Abnormal proliferation of intraergastoplasmic microfilaments in myelinated schwann cells: ultrastructural study of two cases.有髓施万细胞内质网微丝异常增殖:两例超微结构研究
J Neuropathol Exp Neurol. 1982 Jul;41(4):460-5. doi: 10.1097/00005072-198207000-00008.
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