Ruzzier F, Di Gregorio F, Scuka M
Pflugers Arch. 1982 Mar;393(1):121-2. doi: 10.1007/BF00582404.
In a previous study it was observed that prolonged repetitive stimulation (10.s-1) markedly lengthened the time course of the end-plate current. In order to investigate whether this effect could be due to a more dispersed release of the mediator or to a decreased clearance of the mediator from the synaptic cleft, the rise time of the end-plate current and of the miniature end-plate current were analyzed. The results show that presynaptic factors may be involved.
在先前的一项研究中观察到,长时间重复刺激(10次/秒)显著延长了终板电流的时程。为了研究这种效应是由于递质释放更加分散还是由于递质从突触间隙清除减少所致,对终板电流和微小终板电流的上升时间进行了分析。结果表明,可能涉及突触前因素。