山羊维斯纳病毒脑膜脑脊髓炎
Visna virus meningoencephalomyelitis in goats.
作者信息
Sundquist B, Jönsson L, Jacobsson S O, Hammarberg K E
出版信息
Acta Vet Scand. 1981;22(3-4):315-30. doi: 10.1186/BF03548657.
A progressive paresis was encountered in herds of Swedish goats. The symptoms developed during a period of weeks or months, and were initially often seen as a weakness of the hind limbs before the animals became paralytic. The development and the histopathological lesions of the disease in the GNS and the lungs were similar to those of visna in sheep. In vitro grown choroid plexus cells, prepared from affected goats, showed foci of polykaryocytes. Electron microscopy revealed the presence of particles morphologically similar to those of sheep visna virus (SVV). Goats experimentally infected with the goat visna virus (GVV) developed GNS lesions similar to those of visna in sheep and became seropositive to SVV. The results of complement fixation tests, carried out on sera from 11 goat herds, showed a coincidence between seropositiveness and the occurrence of disease in one and the same herd. Using the ELISA method, an average of 80 % of the goats in 5 herds were found to be seropositive to GVV.
在瑞典山羊群中发现了进行性麻痹。症状在数周或数月内逐渐显现，最初常表现为后肢无力，随后动物才会瘫痪。该疾病在山羊神经组织系统（GNS）和肺部的发展及组织病理学病变与绵羊的维斯纳病相似。从患病山羊制备的体外培养脉络丛细胞显示有多核细胞灶。电子显微镜检查发现存在形态上与绵羊维斯纳病毒（SVV）相似的颗粒。用山羊维斯纳病毒（GVV）实验感染的山羊出现了与绵羊维斯纳病相似的GNS病变，并对SVV呈血清学阳性。对11个山羊群血清进行的补体结合试验结果表明，同一羊群中血清阳性与疾病发生存在一致性。使用酶联免疫吸附测定（ELISA）方法，发现5个羊群中平均80%的山羊对GVV呈血清学阳性。
Zotero 插件