Graham J, Whorwell P J, Machin D, Wright R
Hepatogastroenterology. 1981 Oct;28(5):258-60.
Specific lymphocyte transformation to three micro-organisms that have been implicated in Crohn's disease was performed. These were Pseudomonas maltophilia, Mycobacterium kansasii and Rotavirus. No significant differences were observed for any of the antigens tested. Simultaneous testing of nonspecific stimulation by PHA also showed no difference between patients and controls. These results do not support an aetiological role for these organisms mediated by a purely cellular mechanism.
对三种与克罗恩病相关的微生物进行了特异性淋巴细胞转化试验。这三种微生物分别是嗜麦芽窄食单胞菌、堪萨斯分枝杆菌和轮状病毒。在所测试的任何一种抗原中均未观察到显著差异。同时对PHA非特异性刺激的检测也显示患者与对照组之间无差异。这些结果不支持这些微生物通过纯细胞机制介导的病因学作用。
