Farness P L, Schneeman B O
J Nutr. 1982 Jul;112(7):1315-9. doi: 10.1093/jn/112.7.1315.
The present study was undertaken to determine if three sources of dietary fiber would alter length, weight, DNA, protein or enzyme activity in the small intestine since various fibers are known to decrease intestinal absorption. Rats were fed semipurified diets that contained either 20% cellulose (C), 20% oat bran, 5% pectin (P) or no fiber source (FF). Leucine aminopeptidase activity were significantly greater in the P and C groups when compared with the FF group. There were no significant differences in sucrase activity. Animals in the P group had heavier and longer small intestine and heavier mucosa than the FF group. There were no significant differences in total mucosal DNA or protein. These results indicate that two sources of dietary fiber, cellulose and pectin, can change leucine aminopeptidase activity in the small intestine.
本研究旨在确定三种膳食纤维来源是否会改变小肠的长度、重量、DNA、蛋白质或酶活性，因为已知各种纤维会减少肠道吸收。给大鼠喂食含有20%纤维素（C）、20%燕麦麸、5%果胶（P）或无纤维来源（FF）的半纯化日粮。与FF组相比，P组和C组的亮氨酸氨肽酶活性显著更高。蔗糖酶活性没有显著差异。P组动物的小肠比FF组更重、更长，黏膜也更重。总黏膜DNA或蛋白质没有显著差异。这些结果表明，两种膳食纤维来源，即纤维素和果胶，可改变小肠中的亮氨酸氨肽酶活性。
