猴病毒40的小t蛋白是大鼠细胞系中致密病灶形成所必需的。
Small t protein of simian virus 40 is required for dense focus formation in a rat cell line.
作者信息
Sugano S, Yamaguchi N, Shimojo H
出版信息
J Virol. 1982 Mar;41(3):1073-5. doi: 10.1128/JVI.41.3.1073-1075.1982.
Abstract
Incomplete foci were formed in a Fischer rat cell line infected with simian virus 40 detection mutants encoding defective small t antigen. The foci were small and rarely piled up. The fraction of DNA-synthesizing cells in the foci was about half of that induced by wild-type virus.
摘要
在感染了编码缺陷型小t抗原的猿猴病毒40检测突变体的费希尔大鼠细胞系中形成了不完全病灶。这些病灶很小，很少堆积。病灶中进行DNA合成的细胞比例约为野生型病毒诱导比例的一半。
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