Henchal E A, Gentry M K, McCown J M, Brandt W E
Am J Trop Med Hyg. 1982 Jul;31(4):830-6. doi: 10.4269/ajtmh.1982.31.830.
Monoclonal antibodies produced against the four dengue virus serotypes identified four categories of reactions by immunofluorescence: flavivirus group reactive, dengue complex specific, dengue subcomplex specific (DEN-1, DEN-3), and dengue serotype specific. This is the first time that monospecific antibodies have been available for all of these unique antigenic determinants. Hybridoma cell lines producing dengue type-specific antibodies have been deposited in the Hybridoma Cell Bank of the American Type Culture Collection (Rockville, MD) for general distribution.
针对四种登革病毒血清型产生的单克隆抗体，通过免疫荧光鉴定出四类反应：黄病毒属组反应性、登革热复合体特异性、登革热亚复合体特异性（DEN-1、DEN-3）以及登革热血清型特异性。这是首次获得针对所有这些独特抗原决定簇的单特异性抗体。产生登革热型特异性抗体的杂交瘤细胞系已保藏于美国模式培养物集存库（马里兰州罗克维尔）的杂交瘤细胞库，以供广泛分发。
