Sierra Pérez E, Pedrón Giner C, Carrasco Gandía S, Ferro O, de la Loma A, Vázquez González C
An Esp Pediatr. 1982 Mar;16(3):219-28.
A prospective study of 87 children hospital admitted for acute gastroenteritis [AGE] with ages between 24 days and three years and a control group of 32 children with ages between six months and three years, is presented. In all cases a virological study of stools is made by electron microscopy [E/M]. In 63 percent of the 87 patients with AGE, viruses were isolated, being rotavirus the most common, 45.9 percent, a similar incidence as that found in developed countries. The clinical course and analytical findings within the groups with viral and non-viral AGE do not show significant differences. Special stress is set upon the reliability of the E/M technique on the stools for rotavirus induced AGE diagnosis, due to the good correlation with clinical data, presence of seroconversion and the finding of virus in duodenal juice. Results of intestinal biopsy in a certain group of children are shown.
本文介绍了一项前瞻性研究,该研究纳入了87名年龄在24天至3岁之间因急性肠胃炎(AGE)入院的儿童,以及一个由32名年龄在6个月至3岁之间的儿童组成的对照组。所有病例均通过电子显微镜(E/M)对粪便进行病毒学研究。在87例AGE患者中,63%分离出病毒,其中轮状病毒最为常见,占45.9%,这一发病率与发达国家相似。病毒感染性AGE组和非病毒感染性AGE组的临床病程和分析结果无显著差异。由于E/M技术对粪便检测与临床数据、血清转化情况以及十二指肠液中病毒的发现具有良好的相关性,因此特别强调了该技术在轮状病毒引起的AGE诊断中的可靠性。文中还展示了某组儿童的肠道活检结果。