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In vitro susceptibility of Clostridium difficile isolates to cefotaxime, moxalactam, and cefoperazone.艰难梭菌分离株对头孢噻肟、拉氧头孢和头孢哌酮的体外敏感性
Antimicrob Agents Chemother. 1982 May;21(5):846-7. doi: 10.1128/AAC.21.5.846.
2
Comparative synergistic activity of cefoperazone, cefotaxime, moxalactam, and carbenicillin, combined with tobramycin, against Pseudomonas aeruginosa.头孢哌酮、头孢噻肟、拉氧头孢和羧苄西林与妥布霉素联合应用对铜绿假单胞菌的比较协同活性。
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Combination of mezlocillin and azlocillin with cephalosporin antibiotics: cefoxitin, cefoperazone, cefotaxime and moxalactam.
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4
Comparative in vitro activity of moxalactam, cefotaxime, cefoperazone, piperacillin, and aminoglycosides against gram-negative bacilli.羟羧氧酰胺菌素、头孢噻肟、头孢哌酮、哌拉西林和氨基糖苷类药物对革兰氏阴性杆菌的体外活性比较
Antimicrob Agents Chemother. 1980 Oct;18(4):645-8. doi: 10.1128/AAC.18.4.645.
5
[Comparison of antimicrobial activity and stability to beta-lactamases of cefoperazone, cefotaxime, lamoxactam and ceftriaxon].头孢哌酮、头孢噻肟、拉氧头孢及头孢曲松的抗菌活性及对β-内酰胺酶稳定性的比较
Zentralbl Bakteriol Mikrobiol Hyg A Med Mikrobiol Infekt Parasitol. 1982 Jun;252(2):208-21.
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Influence of inoculum size on activity of cefoperazone, cefotaxime, moxalactam, piperacillin, and N-formimidoyl thienamycin (MK0787) against Pseudomonas aeruginosa.接种量对头孢哌酮、头孢噻肟、拉氧头孢、哌拉西林及N-甲酰亚胺硫霉素（MK0787）抗铜绿假单胞菌活性的影响。
Antimicrob Agents Chemother. 1980 Dec;18(6):893-6. doi: 10.1128/AAC.18.6.893.
7
Inoculum size effect on the MIC of cefoperazone, moxalactam, cefotaxime, cefoxitin and cephalothin for 118 strains of Haemophilus influenzae including 'tolerant' micro-organisms.接种量对118株流感嗜血杆菌（包括“耐受”微生物）的头孢哌酮、拉氧头孢、头孢噻肟、头孢西丁和头孢噻吩最低抑菌浓度的影响
J Antimicrob Chemother. 1982 Nov;10(5):397-402. doi: 10.1093/jac/10.5.397.
8
Differences among moxalactam, cefoperazone, and cefotaxime in activity against multiple-antibiotic-resistant gram-negative bacteria.羟羧氧酰胺菌素、头孢哌酮和头孢噻肟对多重耐药革兰氏阴性菌抗菌活性的差异。
Rev Infect Dis. 1982 Nov-Dec;4 Suppl:S516-21. doi: 10.1093/clinids/4.supplement_3.s516.
9
In vitro antimicrobial activity of cefoperazone, cefotaxime, moxalactam (LY127935), azlocillin, mezlocillin, and other beta-lactam antibiotics against Neisseria gonorrhoeae and Haemophilus influenzae, including beta-lactamase-producing strains.头孢哌酮、头孢噻肟、拉氧头孢（LY127935）、阿洛西林、美洛西林及其他β-内酰胺类抗生素对淋病奈瑟菌和流感嗜血杆菌的体外抗菌活性，包括产β-内酰胺酶菌株。
Antimicrob Agents Chemother. 1980 Apr;17(4):757-61. doi: 10.1128/AAC.17.4.757.
10
Comparative in vitro activity of 1-oxa-beta-lactam (LY127935) and cefoperazone with other beta-lactam antibiotics against anaerobic bacteria.1-氧杂-β-内酰胺（LY127935）和头孢哌酮与其他β-内酰胺类抗生素对厌氧菌的体外活性比较
Antimicrob Agents Chemother. 1980 Feb;17(2):129-31. doi: 10.1128/AAC.17.2.129.

引用本文的文献

1
Penicillin Binding Protein Substitutions Cooccur with Fluoroquinolone Resistance in Epidemic Lineages of Multidrug-Resistant Clostridioides difficile.青霉素结合蛋白取代与氟喹诺酮耐药性共同存在于多重耐药艰难梭菌的流行谱系中。
mBio. 2023 Apr 25;14(2):e0024323. doi: 10.1128/mbio.00243-23. Epub 2023 Apr 5.
2
Cefotaxime. A review of its antibacterial activity, pharmacological properties and therapeutic use.头孢噻肟：抗菌活性、药理特性及治疗用途综述
Drugs. 1983 Mar;25(3):223-89. doi: 10.2165/00003495-198325030-00001.

本文引用的文献

1
In vitro susceptibility of Clostridium difficile isolates from patients with antibiotic-associated diarrhea or colitis.来自抗生素相关性腹泻或结肠炎患者的艰难梭菌分离株的体外药敏性。
Antimicrob Agents Chemother. 1980 Apr;17(4):695-8. doi: 10.1128/AAC.17.4.695.
2
Comparative in vitro activity of new beta-lactam antibiotics against anaerobic bacteria.新型β-内酰胺类抗生素对厌氧菌的体外活性比较
Antimicrob Agents Chemother. 1981 Nov;20(5):600-9. doi: 10.1128/AAC.20.5.600.
3
Antimicrobial agents implicated in Clostridium difficile toxin-associated diarrhea of colitis.与艰难梭菌毒素相关的结肠炎腹泻有关的抗菌药物。
Johns Hopkins Med J. 1981 Jul;149(1):6-9.
4
Antimicrobial agent-associated colitis and diarrhea.抗菌药物相关性结肠炎和腹泻
West J Med. 1980 Aug;133(2):115-23.
5
Evaluation of eight cephalosporins in hamster colitis model.八种头孢菌素在仓鼠结肠炎模型中的评估。
Antimicrob Agents Chemother. 1981 Jun;19(6):980-6. doi: 10.1128/AAC.19.6.980.
6
Moxalactam therapy for a wide spectrum of bacterial infections in adults.羟羧氧酰胺菌素治疗成人多种细菌感染。
Antimicrob Agents Chemother. 1981 May;19(5):740-4. doi: 10.1128/AAC.19.5.740.
7
Pharmacokinetics of cefoperazone: a review.
Drugs. 1981;22 Suppl 1:35-45. doi: 10.2165/00003495-198100221-00010.
8
Worldwide clinical experience with cefoperazone.头孢哌酮的全球临床经验。
Drugs. 1981;22 Suppl 1:108-18. doi: 10.2165/00003495-198100221-00022.
9
Pharmacokinetics of moxalactam in subjects with normal and impaired renal function.正常肾功能和肾功能受损受试者中莫拉卡坦的药代动力学。
Antimicrob Agents Chemother. 1981 Jun;19(6):965-71. doi: 10.1128/AAC.19.6.965.
10
Cephalosporin-associated pseudomembranous colitis.头孢菌素相关性假膜性结肠炎
JAMA. 1976 Aug 23;236(8):948-9.

艰难梭菌分离株对头孢噻肟、拉氧头孢和头孢哌酮的体外敏感性

In vitro susceptibility of Clostridium difficile isolates to cefotaxime, moxalactam, and cefoperazone.

作者信息

Greenfield R A, Kurzynski T A, Craig W A

出版信息

Antimicrob Agents Chemother. 1982 May;21(5):846-7. doi: 10.1128/AAC.21.5.846.

DOI:10.1128/AAC.21.5.846
PMID:6285817
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC182026/
Abstract

The in vitro susceptibility of 20 isolates of Clostridium difficile to cefotaxime, moxalactam, and cefoperazone was determined by a standard agar dilution method. The median minimal inhibitory concentrations were 64, 32, and 32 mug/ml for cefotaxime, moxalactam, and cefoperazone, respectively.

摘要

采用标准琼脂稀释法测定了20株艰难梭菌对头孢噻肟、拉氧头孢和头孢哌酮的体外敏感性。头孢噻肟、拉氧头孢和头孢哌酮的最低抑菌浓度中位数分别为64、32和32μg/ml。