Richter I, Weber N
Hoppe Seylers Z Physiol Chem. 1981 Aug;362(8):1163-6.
The pattern of incorporation of isomeric cis-[1-14C]octadecen-1-ols into alkyl moieties of glycerophospholipids of rat brain as well as of L 1210 and S 180 murine ascites cells revealed the following: 1) The enzymes involved in the biosynthesis of acylalkylglycerophospholamines have no substrate specificity with regard to position of the double bond of either cis-oectadecen-1-ols or of intermediate ether lipids derived therefrom. 2) CDPcholine: diradylglycerol cholinephosphotransferases exhibit a strong preference for acylalkylglycerols with cis-8, cis-9 and cis-10-octadecenyl moieties as substrates.
异构顺式-[1-¹⁴C]十八碳烯-1-醇掺入大鼠脑以及L 1210和S 180小鼠腹水细胞甘油磷脂烷基部分的模式显示如下：1）参与酰基烷基甘油磷酸胺生物合成的酶对顺式十八碳烯-1-醇或由此衍生的中间醚脂双键位置没有底物特异性。2）CDP胆碱：二酰基甘油胆碱磷酸转移酶表现出强烈偏好以具有顺式-8、顺式-9和顺式-10-十八碳烯基部分的酰基烷基甘油作为底物。
