Mortimer G, Gibson A A
J Clin Pathol. 1982 Aug;35(8):849-54. doi: 10.1136/jcp.35.8.849.
Seven cases of recurring digital fibroma were seen over a 35-year period. All demonstrated the classical clinical, macroscopic, and microscopic features of this distinct tumour, including the pathognomonic round, eosinophilic cytoplasmic inclusion bodies. Ultrastructurally, all seven cases were confirmed to be myofibroblastic in nature, and the morphology and intracellular topography of the inclusion bodies suggested their derivation from contractile protein. These findings establish recurring digital fibroma as a neoplastic lesion of the myofibroblast.
在35年的时间里共发现7例复发性指纤维瘤。所有病例均表现出这种独特肿瘤典型的临床、大体及显微镜下特征，包括具有诊断意义的圆形嗜酸性胞质包涵体。超微结构上，所有7例病例均被证实本质上为肌成纤维细胞性，且包涵体的形态及细胞内分布表明其源自收缩蛋白。这些发现确立了复发性指纤维瘤为肌成纤维细胞的肿瘤性病变。
