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单纯疱疹病毒mRNA种类在EcoRI片段I中的定位。

Herpes simplex virus mRNA species mapping in EcoRI fragment I.

作者信息

Hall L M, Draper K G, Frink R J, Costa R H, Wagner E K

出版信息

J Virol. 1982 Aug;43(2):594-607. doi: 10.1128/JVI.43.2.594-607.1982.

DOI:10.1128/JVI.43.2.594-607.1982
PMID:6287033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC256162/
Abstract

We described the detailed characterization and high-resolution mapping of nine herpes simplex virus type 1 mRNAs encoded in EcoRI fragment I. Four of these mRNAs are partially colinear and encode the same sized polypeptide in vitro. Nucleotide sequence analysis of the DNA around the 5' ends of these mRNAs suggested that the larger may encode a small (ca. 100-dalton) polypeptide not resolvable by in vitro translation.

摘要

我们描述了在EcoRI片段I中编码的9种1型单纯疱疹病毒mRNA的详细特征和高分辨率定位。其中4种mRNA部分共线性，并且在体外编码相同大小的多肽。对这些mRNA 5'端周围DNA的核苷酸序列分析表明，较大的mRNA可能编码一种在体外翻译时无法分辨的小（约100道尔顿）多肽。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/e5c7e6739a07/jvirol00155-0247-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/f54645b95efc/jvirol00155-0238-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/5e84cdd5f1c3/jvirol00155-0240-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/06b344dd4ec7/jvirol00155-0242-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/d3d143d7809e/jvirol00155-0243-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/b9477f221b0a/jvirol00155-0244-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/e5c7e6739a07/jvirol00155-0247-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/f54645b95efc/jvirol00155-0238-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/5e84cdd5f1c3/jvirol00155-0240-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/06b344dd4ec7/jvirol00155-0242-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/d3d143d7809e/jvirol00155-0243-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/b9477f221b0a/jvirol00155-0244-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fede/256162/e5c7e6739a07/jvirol00155-0247-a.jpg

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本文引用的文献

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Proc Natl Acad Sci U S A. 1981 Oct;78(10):6139-43. doi: 10.1073/pnas.78.10.6139.
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Identification of a virus-specific polypeptide associated with a transforming fragment (BglII-N) of herpes simplex virus type 2 DNA.鉴定与2型单纯疱疹病毒DNA的转化片段（BglII-N）相关的病毒特异性多肽。
J Virol. 1981 Oct;40(1):126-32. doi: 10.1128/JVI.40.1.126-132.1981.
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Analysis of transcriptional regulatory signals of the HSV thymidine kinase gene: identification of an upstream control region.
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Mol Cell Proteomics. 2013 Nov;12(11):3237-52. doi: 10.1074/mcp.M113.030866. Epub 2013 Aug 12.
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Temporal regulation of herpes simplex virus type 2 VP22 expression and phosphorylation.单纯疱疹病毒2型VP22表达与磷酸化的时间调控
J Virol. 2001 Nov;75(22):10721-9. doi: 10.1128/JVI.75.22.10721-10729.2001.
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Herpes simplex virus type 1 entry is inhibited by the cobalt chelate complex CTC-96.单纯疱疹病毒1型的进入受到钴螯合物复合物CTC-96的抑制。
J Virol. 2001 May;75(9):4117-28. doi: 10.1128/JVI.75.9.4117-4128.2001.
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