SV40大T抗原基因的一个片段具有转化作用。 - Suppr

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超能文献

A fragment of the SV40 large T-antigen gene transforms.

作者信息

Clayton C E, Murphy D, Lovett M, Rigby P W

出版信息

Nature. 1982 Sep 2;299(5878):59-61. doi: 10.1038/299059a0.

DOI:10.1038/299059a0

PMID:6287280

Abstract

摘要

相似文献

A fragment of the SV40 large T-antigen gene transforms.SV40大T抗原基因的一个片段具有转化作用。

Nature. 1982 Sep 2;299(5878):59-61. doi: 10.1038/299059a0.

SV40 early mutants that are defective for viral DNA synthesis but competent for transformation of cultured rat and simian cells.SV40早期突变体，其病毒DNA合成存在缺陷，但能够转化培养的大鼠和猴细胞。

Virology. 1982 Nov;123(1):78-92. doi: 10.1016/0042-6822(82)90296-3.

Host-virus interactions critical for cellular transformation by polyoma virus and SV40.宿主-病毒相互作用对多瘤病毒和SV40诱导细胞转化至关重要。

Cold Spring Harb Symp Quant Biol. 1980;44 Pt 1,:333-42. doi: 10.1101/sqb.1980.044.01.038.

T antigens of SV40-transformed cells.猴空泡病毒40（SV40）转化细胞的T抗原

Cold Spring Harb Symp Quant Biol. 1980;44 Pt 1,:171-8. doi: 10.1101/sqb.1980.044.01.020.

Characterization of a gene encoding a 115 K super T antigen expressed by a SV40-transformed rat cell line.对由SV40转化的大鼠细胞系表达的编码115K超级T抗原的基因的表征。

Nucleic Acids Res. 1981 Aug 25;9(16):4111-28. doi: 10.1093/nar/9.16.4111.

Production of a T-antigen-related protein in mammalian cells after stable transformation with a cloned SV40 gene fragment.用克隆的SV40基因片段进行稳定转化后，哺乳动物细胞中产生T抗原相关蛋白。

Hoppe Seylers Z Physiol Chem. 1982 Apr;363(4):445-8.

Monkey cells transformed by SV40 DNA fragments: flat revertants synthesize large and small T antigens.由SV40 DNA片段转化的猴细胞：扁平回复突变体合成大T抗原和小T抗原。

Cold Spring Harb Symp Quant Biol. 1980;44 Pt 1,:605-10. doi: 10.1101/sqb.1980.044.01.063.

Linkage relationship between TK and SV40 T-antigen genes in the SV40-transformed WI98VaD human cell line.SV40转化的WI98VaD人细胞系中TK与SV40 T抗原基因之间的连锁关系。

Exp Cell Res. 1980 Sep;129(1):127-32. doi: 10.1016/0014-4827(80)90337-7.

Enhanced metastasis of tumours induced by a SV40 small T deletion mutant.由SV40小T缺失突变体诱导的肿瘤转移增强。

Nature. 1982 Apr 15;296(5858):672-5. doi: 10.1038/296672a0.

Viral and cellular control of the SV40-transformed phenotype.SV40转化表型的病毒和细胞调控

Cold Spring Harb Symp Quant Biol. 1980;44 Pt 1,:343-52. doi: 10.1101/sqb.1980.044.01.039.

引用本文的文献

The amino-terminal transforming region of simian virus 40 large T and small t antigens functions as a J domain.猴病毒40大T抗原和小t抗原的氨基末端转化区作为一个J结构域发挥作用。

Mol Cell Biol. 1997 Aug;17(8):4761-73. doi: 10.1128/MCB.17.8.4761.

Independent expression of the transforming amino-terminal domain of SV40 large I antigen from an alternatively spliced third SV40 early mRNA.来自剪接变异的第三个SV40早期mRNA的SV40大T抗原转化性氨基末端结构域的独立表达。

EMBO J. 1993 Dec;12(12):4739-46. doi: 10.1002/j.1460-2075.1993.tb06162.x.

Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity.猿猴病毒40小t抗原与丝裂原活化激酶协同作用以刺激活化蛋白-1的活性。

Mol Cell Biol. 1994 Sep;14(9):6244-52. doi: 10.1128/mcb.14.9.6244-6252.1994.

Polyoma middle T antigen requires cooperation from another gene to express the malignant phenotype in vivo.多瘤病毒中T抗原在体内表达恶性表型需要另一个基因的协同作用。

Mol Cell Biol. 1984 Apr;4(4):755-60. doi: 10.1128/mcb.4.4.755-760.1984.

Large-T-antigen-p53 complex formation is not cold sensitive in a cold-sensitive transformant induced by simian virus 40 mutant tsA1499.在由猴病毒40突变体tsA1499诱导的冷敏感转化体中，大T抗原-p53复合物的形成对温度不敏感。

J Virol. 1984 Mar;49(3):997-1001. doi: 10.1128/JVI.49.3.997-1001.1984.

Expression of the large T protein of polyoma virus promotes the establishment in culture of "normal" rodent fibroblast cell lines.多瘤病毒大T蛋白的表达促进了“正常”啮齿动物成纤维细胞系在培养中的建立。

Proc Natl Acad Sci U S A. 1983 Jul;80(14):4354-8. doi: 10.1073/pnas.80.14.4354.

Simian virus 40 deletion mutants that transform with reduced efficiency.转化效率降低的猿猴病毒40缺失突变体。

Mol Cell Biol. 1983 Mar;3(3):484-9. doi: 10.1128/mcb.3.3.484-489.1983.

Stabilization of the 53,000-dalton nonviral tumor antigen is not required for transformation by simian virus 40.猿猴病毒40转化并不需要稳定53,000道尔顿的非病毒肿瘤抗原。

Mol Cell Biol. 1983 Feb;3(2):290-6. doi: 10.1128/mcb.3.2.290-296.1983.

Structure and synthesis of a simian virus 40 super T-antigen.猿猴病毒40大T抗原的结构与合成

J Virol. 1982 Dec;44(3):963-73. doi: 10.1128/JVI.44.3.963-973.1982.

Monoclonal antibodies against simian virus 40 nuclear large T tumour antigen: epitope mapping, papova virus cross-reaction and cell surface staining.抗猿猴病毒40核大T肿瘤抗原的单克隆抗体：表位定位、乳头多瘤空泡病毒交叉反应及细胞表面染色

EMBO J. 1984 Jul;3(7):1485-91. doi: 10.1002/j.1460-2075.1984.tb02000.x.

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