Vachálková A, Benesová M, Bahna L
Neoplasma. 1982;29(2):161-7.
The authors have studied the electrochemical behavior of a series of carcinogenic and inactive heterocyclic compounds in anhydrous medium in the presence of a proton-donor. As anhydrous medium the authors used anhydrous dimethylformamide as proton-donor phenol. In the presence of proton-donor there had occurred on polarographic reduction of the employed carcinogenic heterocyclic compounds changes in the number of polarographic waves. Between the two original waves in these compounds there arose in the presence of phenol a new wave. In non-carcinogenic heterocyclic compounds such an effect of phenol was not noted. In the present paper the authors discuss the possible mechanism of electroreduction of carcinogenic and inactive heterocyclic compounds in anhydrous medium in the presence of a proton-donor.
作者们研究了一系列致癌和非活性杂环化合物在无水介质中、在质子供体存在下的电化学行为。作者们使用无水二甲基甲酰胺作为无水介质，以苯酚作为质子供体。在质子供体存在的情况下，所采用的致癌杂环化合物的极谱还原过程中极谱波的数量发生了变化。在这些化合物的两个原始波之间，在苯酚存在时出现了一个新波。在非致癌杂环化合物中未观察到苯酚的这种效应。在本文中，作者们讨论了在无水介质中、在质子供体存在下致癌和非活性杂环化合物的电还原可能机制。
