Massey E W, Moore J, Schold S C
Neurology. 1981 Oct;31(10):1277-81. doi: 10.1212/wnl.31.10.1277.
Nineteen patients with mental neuropathy secondary to systemic cancer are described. In nine patients, the numb chin was the presenting symptom of a neoplasm. Nine patients had lymphoreticular malignancies, and the others had a variety of solid tumors. Radiograms of the mandible were abnormal in 5 of 12 patients. The cerebrospinal fluid contained malignant cells in two. Resolution, complete or partial, occurred in 16 of 19 patients receiving radiation or chemotherapy, including 8 who received chemotherapy alone. Sixteen of the 19 patients died within 17 months of the onset of the neuropathy. A nontraumatic mental neuropathy should initiate a search for cancer.
本文描述了19例继发于全身性癌症的精神神经病患者。9例患者中，麻木性下巴是肿瘤的首发症状。9例患者患有淋巴网状系统恶性肿瘤，其他患者患有各种实体瘤。12例患者中有5例下颌骨X线片异常。2例患者的脑脊液中含有恶性细胞。19例接受放疗或化疗的患者中有16例完全或部分缓解，其中8例仅接受了化疗。19例患者中有16例在神经病发作后的17个月内死亡。非创伤性精神神经病应引发对癌症的排查。
