The conalbumin "TATA" box sequence and the SV40 72 base-pair repeat region influence expression of a chimeric gene in vivo.
作者信息
Wasylyk B, Gaub M P, Dierich A, Wasylyk C, Chambon P
出版信息
Prog Clin Biol Res. 1982;85 Pt A:13-24.
PMID:6287480
Abstract
摘要
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A novel eukaryotic promoter element: the simian virus 40 72 base pair repeat.一种新型真核启动子元件：猿猴病毒40 72碱基对重复序列。
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The SV40 72 bp repeat preferentially potentiates transcription starting from proximal natural or substitute promoter elements.SV40 72碱基对重复序列优先增强从近端天然或替代启动子元件起始的转录。
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Organization and sequence studies of the 17-piece chicken conalbumin gene.17片段鸡伴白蛋白基因的组织与序列研究
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Specific in vitro transcription of conalbumin gene is drastically decreased by single-point mutation in T-A-T-A box homology sequence.伴清蛋白基因的特异性体外转录因T-A-T-A盒同源序列中的单点突变而急剧减少。
Proc Natl Acad Sci U S A. 1980 Dec;77(12):7024-8. doi: 10.1073/pnas.77.12.7024.
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Short and long range activation by the SV40 enhancer.SV40增强子的短程和长程激活
Nucleic Acids Res. 1984 Jul 25;12(14):5589-608. doi: 10.1093/nar/12.14.5589.
8
A T to A base substitution and small deletions in the conalbumin TATA box drastically decrease specific in vitro transcription.伴清蛋白TATA框中的A到T碱基替换和小片段缺失显著降低了体外特异性转录。
Nucleic Acids Res. 1981 Apr 24;9(8):1813-24. doi: 10.1093/nar/9.8.1813.
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Stimulation of in vitro transcription from heterologous promoters by the simian virus 40 enhancer.猿猴病毒40增强子对异源启动子体外转录的刺激作用。
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10
Definition of the simian virus 40 early promoter region and demonstration of a host range bias in the enhancement effect of the simian virus 40 72-base-pair repeat.猿猴病毒40早期启动子区域的定义以及猿猴病毒40 72碱基对重复序列增强效应中宿主范围偏向性的证明。
Proc Natl Acad Sci U S A. 1983 Feb;80(3):721-5. doi: 10.1073/pnas.80.3.721.
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