Jung F, Reiss D, Sibilly A
Sem Hop. 1982 Jun 3;58(22):1349-53.
Acute primary ulcer of the small intestine is an exceptional occurrence. Diagnosis is established only after a complication occurs. In most instances, this complication is perforation of the gut. Acute primary ulcer of the small intestine is accurately defined by specific histologic criteria. It can be unequivocally distinguished from the many other causes of spontaneous perforation of the small intestine. Experimental studies, although numerous, have not improved understanding of pathophysiology. Nosologic classification remains unclear. Many features are similar to those encountered in acute peptic ulcer but stress is usually absent. Other features resemble those of transient necrotizing enterocolitis ; acute primary ulcer of the small intestine may be a very localized form of this latter condition. Ischemia seems to be the most significant factor. However, for an ulcer and finally perforation to occur, ischemia must probably be associated with a number of other factors.
急性原发性小肠溃疡是一种罕见的病症。只有在出现并发症后才能确诊。在大多数情况下，这种并发症是肠道穿孔。急性原发性小肠溃疡可通过特定的组织学标准准确界定。它可以明确地与小肠自发性穿孔的许多其他原因区分开来。尽管有大量的实验研究，但对其病理生理学的理解并未得到改善。疾病分类仍然不明确。许多特征与急性消化性溃疡相似，但通常不存在应激因素。其他特征类似于短暂性坏死性小肠结肠炎；急性原发性小肠溃疡可能是后者的一种非常局限的形式。缺血似乎是最重要的因素。然而，要发生溃疡并最终穿孔，缺血可能必须与许多其他因素相关。
