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Limits of usefulness of electrophysiological methods for estimating dendritic length in neurones.

作者信息

de Jongh H R, Kernell D

出版信息

J Neurosci Methods. 1982 Jul;6(1-2):129-38. doi: 10.1016/0165-0270(82)90023-1.

DOI:10.1016/0165-0270(82)90023-1
PMID:6289016
Abstract

The present report deals with methodological problems concerning the electrophysiological analysis of multipolar neurones. In a nerve cell in which the dendrites may be considered as being equivalent to a single cable, the electrotonic length of the equivalent cable may be determined by analyzing the potential response to a step of current injected into the soma (Rall, 1969). In the present model study it is shown that this kind of analysis is unsuitable for discriminating between neurones with different dendritic lengths in excess of about 1.5-2.0 length constants.

摘要

相似文献

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Limits of usefulness of electrophysiological methods for estimating dendritic length in neurones.
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引用本文的文献

1
Synaptic signaling in an active central network only moderately changes passive membrane properties.在活跃的中枢网络中,突触信号传导仅适度改变被动膜特性。
Proc Natl Acad Sci U S A. 1998 Aug 18;95(17):10251-6. doi: 10.1073/pnas.95.17.10251.
2
Modeling the electrical behavior of anatomically complex neurons using a network analysis program: passive membrane.使用网络分析程序对解剖学上复杂的神经元的电行为进行建模:被动膜
Biol Cybern. 1985;53(1):27-40. doi: 10.1007/BF00355688.
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Dendrites of cat's spinal motoneurones: relationship between stem diameter and predicted input conductance.
猫脊髓运动神经元的树突:干直径与预测输入电导之间的关系
J Physiol. 1989 Jun;413:255-69. doi: 10.1113/jphysiol.1989.sp017652.