Adekunle O O, Osanyintuyi S O, Ayeni O
Afr J Med Med Sci. 1982 Sep-Dec;10(3-4):69-71.
The results of gastric stimulation using varying doses of pentagastrin in twenty-five Nigerians (twenty cases of duodenal ulcer and five controls) are presented. Doses used were 4, 6, 8, and 10 micrograms/kg bodyweight. The optimal response was obtained using 6 micrograms/kg bodyweight in the test cases while the maximum acid output (MAO) was 15.14 mEq/hr (19 mEq/hr in males, 12.50 mEq/hr in females). The recommended dose for optimal response in Caucasians is 6 micrograms/kg bodyweight which correlates with the dose in our patients. However, the maximum acid output at this dose is higher in Caucasians.
本文展示了对25名尼日利亚人（20例十二指肠溃疡患者和5名对照者）使用不同剂量的五肽胃泌素进行胃刺激的结果。使用的剂量为4、6、8和10微克/千克体重。在测试病例中，使用6微克/千克体重可获得最佳反应，而最大酸排量（MAO）为15.14毫当量/小时（男性为19毫当量/小时，女性为12.50毫当量/小时）。高加索人获得最佳反应的推荐剂量为6微克/千克体重，这与我们患者使用的剂量相关。然而，高加索人在该剂量下的最大酸排量更高。
