Posokhova E A
Vopr Pitan. 1978 Jan-Feb(1):27-32.
In tests staged on albino rats with acute dystrophy of the liver provoked with carbon tetrachloride the effect of orotic acid and calcium pangamate on the functional state of the liver was studied. Combined application of orotic acid and calcium pangamate was found to promote a more complete restoration of an intensive secretion of bile, synthesis and secretion of cholates together with bile, formation and secretion of bilirubin, excretion of cholesterol than this could be achieved by separate application of these compounds.
在用四氯化碳诱发白化大鼠急性肝营养不良的实验中,研究了乳清酸和泛酸钙对肝脏功能状态的影响。结果发现,与单独使用这些化合物相比,联合使用乳清酸和泛酸钙能更全面地促进胆汁大量分泌、胆酸盐与胆汁的合成与分泌、胆红素的形成与分泌以及胆固醇的排泄的恢复。