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小剂量天然放射性(氡)对慢性风湿病中DNA合成及DNA修复的影响

[DNA-synthesis and DNA-repair in chronic rheumatism influenced by small doses of natural radioactivity (radon)].

作者信息

Günther R, Altmann H

出版信息

Z Rheumatol. 1978 Jan-Feb;37(1-2):17-22.

PMID:629091
Abstract

Elevated natural radioactivity during a treatment at Badgastein (Austria) caused an increase in DNA-repair of lymphocytes of patients with ankylosing spondylitis and osteoarthritis. Semiconservative DNA-synthesis was remarkably lower after the treatment in patients with ankylosing spondylitis and a small decrease was obtained also in lymphocytes of osteoarthritis patients. These effects are discussed in relation to late effects.

摘要

奥地利巴德加施泰因的一次治疗期间自然放射性升高,导致强直性脊柱炎和骨关节炎患者淋巴细胞的DNA修复增加。治疗后,强直性脊柱炎患者的半保留DNA合成显著降低,骨关节炎患者的淋巴细胞也有小幅下降。针对这些影响与晚期效应进行了讨论。

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