[Mode of action of D-penicillamine in chronic polyarthritis. 1. Protein synthesis inhibition in synovial fluid cells].

The influence of D-Penicillamine on protein synthesis in synovial fluid cells was investigated in 5 patients suffering from rheumatoid arthritis. Intra-articular injection of this substance at a dosage of 5 to 250 mg is followed by an inhibition of protein synthesis in the synovial fluid cells.