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[Mode of action of D-penicillamine in chronic polyarthritis. 2. Studies on DNA repair in synovial fluid cells following intra-articular administration of D-penicillamine].

作者信息

Bröll H, Altmann H, Kocsis F, Klein W

出版信息

Z Rheumatol. 1978 Jan-Feb;37(1-2):56-9.

PMID:629097
Abstract

6 patients with rheumatoid arthritis were treated intraarticularly with 50 or 100 mg D-Penicillamine. The influence of this substance on DNA repair in cells of synovial fluid was investigated. DNA repair was investigated by gradient centrifugation. 50 mg D-PA showed no effect, 100 mg D-PA a slight slowing of the DNA-rejoining till the native supercoiled DNA form.

摘要

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