Fedorova M L
Zh Nevropatol Psikhiatr Im S S Korsakova. 1978;78(1):35-41.
The author conducted a clinico-electrophysiological study of 350 patients with migraine. In 12.5% of the patients there were cases with a loss of consciousness. The conclusion is made that in combination of one attack of symptoms of migraine and epilepsy they have one pathogenesis: vasomotor disorders evoking both migrainose crises and syncopes with a convulsive syndrome. Quite typical of such conditions are precursors, massive vegetative disturbances, a tonic character of the convulsions. A loss of consciousness in the intra-attack period may be assessed as a syncope, mainly of orthostatic and vaso-vagal type; a loss of consciousness during the attack--as a syncope connected with migrainose disorders of cerebral hemodynamics. In alternation of migrainose and epileptical attacks it is claimed that there is a combination of 2 diseases. The conclusion is made that a loss of consciousness in migraine and epilepsy are different not only by clinical signs, but by its pathogenesis. This fact determines the preventive therapy of both diseases.
作者对350例偏头痛患者进行了临床电生理研究。12.5%的患者存在意识丧失情况。得出的结论是,偏头痛症状与癫痫发作一次同时出现时,它们有共同的发病机制:血管运动障碍引发偏头痛发作和伴有惊厥综合征的晕厥。这类情况的典型特征包括先兆、大量自主神经功能紊乱、惊厥的强直性质。发作期的意识丧失可被评估为晕厥,主要是体位性和血管迷走神经性晕厥;发作时的意识丧失——是与偏头痛性脑血流动力学紊乱相关的晕厥。在偏头痛发作与癫痫发作交替出现时,有人认为这是两种疾病的合并。得出的结论是,偏头痛和癫痫中的意识丧失不仅在临床体征上不同,其发病机制也不同。这一事实决定了这两种疾病的预防性治疗。