Identification of polypeptide precursors to HSV-1 glycoproteins by cell-free translation.

Using antisera of limited specificity we have detected among the in vitro translation products of HSV-1 RNA, polypeptides antigenically related to infected cell glycoproteins. The results obtained suggest that non-glycosylated polypeptide precursors of mol. wt. 85,000 and 52,000 correspond to infected cell glycoproteins of mol. wt. 120,000 to 126,000 and 56,000 to 68,000 respectively.