Stys S J, Clewell W H, Meschia G
Am J Obstet Gynecol. 1978 Feb 15;130(4):414-8. doi: 10.1016/0002-9378(78)90282-x.
A new animal model has been developed to measure intrinsic changes of cerivcal compliance during spontaneous parturition or exposure to hormonal manipulation. Intermittent measurements of cervical compliance and continous measurements of uterine and cervical pressure were made during the last month of gestation of nine pregnant ewes. Cervical compliance increased abruptly and dramatically during spontanous and dexamethasone-induced parturition. Maternal progesterone supplementation at parturition inhibited uterine contractions but not the increase in cervical compliance, demonstrating the independence of the two events. The cervix was found to contract rhythmically and vigorously with a gradual decrease in activity as parturition approached.
一种新的动物模型已被开发出来,用于测量自然分娩或激素处理过程中宫颈顺应性的内在变化。在九只怀孕母羊妊娠的最后一个月,间歇性测量宫颈顺应性,并连续测量子宫和宫颈压力。在自然分娩和地塞米松诱导的分娩过程中,宫颈顺应性急剧且显著增加。分娩时母体补充孕酮可抑制子宫收缩,但不抑制宫颈顺应性的增加,这表明这两个事件是独立的。发现宫颈有节律且强烈地收缩,随着分娩临近,活动逐渐减少。