Schwartz S E, Levine G D, Starr C M
Am J Clin Nutr. 1982 Dec;36(6):1102-5. doi: 10.1093/ajcn/36.6.1102.
The effect of short-term fiber ingestion on jejunal ion fluxes was evaluated in rats using a standard Ussing chamber technique. Ingestion of cellulose and pectin decreased the mucosal to serosal fluxes of both Na and Cl but did not significantly alter serosal to mucosal fluxes; net fluxes of both Na and Cl were significantly lower in the group supplemented with dietary fiber as compared to those animals fed a fiber-free diet. Both potential difference and short-circuit current were higher in the fiber-free group than in the group supplemented with dietary fiber; tissue conductance, however, was unaffected by fiber ingestion. The residual flux of all three groups was virtually identical suggesting that electrical alterations observed after cellulose and pectin ingestion are not the result of ion fluxes other than Na and Cl. These data, coupled with previous observations that short-term fiber supplementation impairs glucose and leucine absorption, suggest that fiber ingestion alters the intestinal membrane, specifically sites of active transport.
采用标准的尤斯灌流小室技术，在大鼠中评估了短期摄入纤维对空肠离子通量的影响。摄入纤维素和果胶可降低钠和氯从黏膜到浆膜的通量，但对从浆膜到黏膜的通量没有显著影响；与喂食无纤维饮食的动物相比，补充膳食纤维组的钠和氯净通量显著更低。无纤维组的电位差和短路电流均高于补充膳食纤维组；然而，组织电导不受纤维摄入的影响。三组的残余通量几乎相同，这表明摄入纤维素和果胶后观察到的电变化不是钠和氯以外离子通量的结果。这些数据，再加上之前观察到的短期补充纤维会损害葡萄糖和亮氨酸吸收，表明摄入纤维会改变肠膜，特别是主动转运位点。
