Scher J, Bottone E, Desmond E, Simons W
Am J Obstet Gynecol. 1982 Dec 15;144(8):906-9. doi: 10.1016/0002-9378(82)90182-x.
In a prospective study of an obstetric population, 28 of 488 (4%) routine asymptomatic patients had positive cultures for herpes simplex virus from their genital tract. Cesarean section was carried out if the virus was present in the genital tract at the time of delivery. In one instance, a culture which had reverted to negative became positive again. No cases of neonatal herpes were reported in the time of the study. As yet, the infectivity of these subclinical cases is unclear, and the incidence of neonatal herpes is not as high as would be expected from the study. Further studies need to be carried out to evaluate the exact risk of the asymptomatic herpesvirus shedder to the infant at birth.
在一项针对产科人群的前瞻性研究中,488名常规无症状患者中有28名(4%)生殖道单纯疱疹病毒培养呈阳性。如果分娩时生殖道存在该病毒,则进行剖宫产。有一例中,原本转阴的培养物再次转为阳性。研究期间未报告新生儿疱疹病例。目前,这些亚临床病例的传染性尚不清楚,且新生儿疱疹的发病率并未如研究预期的那样高。需要进一步开展研究,以评估无症状疱疹病毒携带者在婴儿出生时对其造成的确切风险。