Kerr T P, Ross M D, Ernst S A
Am J Otolaryngol. 1982 Sep-Oct;3(5):332-8. doi: 10.1016/s0196-0709(82)80006-9.
Cytochemical and autoradiographic procedures were employed to determine the cellular distribution of Na+,K+-ATPase in the guinea pig cochlea. The highest activity was associated with the stria vascularis and was restricted almost entirely to the contraluminal extensions of the marginal cells. Elevated levels of activity were also observed in stromal cells of the spiral prominence, external sulcus, and spiral limbus. The pattern of activity in the latter tissues was unusual in being symmetrically distributed along the plasma membranes of the reactive cells. In the organ of Corti, only neural elements showed appreciable activity. Possible functions of the enzyme are discussed in relation to cochlear fluid balance.
采用细胞化学和放射自显影方法来确定豚鼠耳蜗中Na +，K + -ATP酶的细胞分布。最高活性与血管纹相关，并且几乎完全局限于边缘细胞的对腔延伸部分。在螺旋隆起、外沟和螺旋缘的基质细胞中也观察到活性水平升高。后一组组织中的活性模式不同寻常，因为它沿着反应性细胞的质膜对称分布。在柯蒂氏器中，只有神经元成分显示出明显的活性。结合耳蜗内液体平衡讨论了该酶可能的功能。
