Fredricsson B
Andrologia. 1978 Jan-Feb;10(1):43-8. doi: 10.1111/j.1439-0272.1978.tb01312.x.
morphologic comparisons of the live and dead sperm population gives information concerning non-lethal and lethal abnormalities. Many of the abnormalities of the sperm heads and midpieces and in particular enlarged heads belong to the latter group. On the other hand, tapering of the head, cytoplasmic droplets and abnormal tails have littel lethal significance. Depletion of the extra-gonadal sperm reserve does not affect the morphology of neither the living nor the dead spermatozoa. This indicates that no significant abnormalities develop after sperm maturation within the epididymis. Cyproterone acetate was shown to affect midpieces and fails of the living spermatozoa within two weeks of treatment indicating an effect on the epididymal level, whereas abnormal heads increase after four weeks indicating an effect on the germinative epithelium, not before the spermatid stage.
对活精子和死精子群体进行形态学比较，可提供有关非致死性和致死性异常的信息。精子头部和中段的许多异常，特别是头部增大，属于后一组。另一方面，头部变细、细胞质滴和异常尾部的致死意义不大。性腺外精子储备的消耗对活精子和死精子的形态均无影响。这表明精子在附睾内成熟后不会出现明显异常。已表明醋酸环丙孕酮在治疗两周内会影响活精子的中段和尾部，表明对附睾水平有影响，而四周后异常头部增加，表明对生精上皮有影响，且在精子细胞阶段之前不会有影响。
