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诱导超数排卵处理后小母牛血浆中游离雌激素和结合雌激素浓度的变化及其与排卵数的关系。

Changes in the plasma concentrations of free and conjugated oestrogens in heifers after treatment to induce superovulation and the relationship with number of ovulations.

作者信息

Saumande J, Lopez-Sebastian A

出版信息

J Reprod Fertil. 1982 Nov;66(2):411-6. doi: 10.1530/jrf.0.0660411.

DOI:10.1530/jrf.0.0660411
PMID:6294293
Abstract

Oestradiol-17 beta and conjugated oestrone, oestradiol-17 beta and oestradiol-17 alpha were measured in peripheral plasma of heifers treated with PMSG/PGF-2 alpha to induce superovulation. Changes in the concentrations of each hormone were synchronous, the highest level being near oestrus. For a given number of ovulations the hormone with the highest concentration was total oestradiol-17 alpha, then came total oestrone, total oestradiol-17 beta and oestradiol-17 beta. For each oestrogen, the maximum preovulatory concentration measured was significantly correlated with the number of ovulations; the regression line for total oestradiol-17 alpha was twice as steep as that for oestradiol-17 beta. It is concluded that in animals treated to induce superovulation assay of total oestradiol-17 alpha gives a better induction of the number of follicles induced to ovulate than does the more conventional assay of oestradiol-17 beta.

摘要

对用孕马血清促性腺激素/前列腺素F-2α处理以诱导超排卵的小母牛外周血浆中的17β-雌二醇、结合雌酮、17β-雌二醇和17α-雌二醇进行了测定。每种激素浓度的变化是同步的,最高水平接近发情期。对于给定的排卵数,浓度最高的激素是总17α-雌二醇,其次是总雌酮、总17β-雌二醇和17β-雌二醇。对于每种雌激素,测得的排卵前最大浓度与排卵数显著相关;总17α-雌二醇的回归线斜率是17β-雌二醇的两倍。得出的结论是,在经处理诱导超排卵的动物中,与更传统的17β-雌二醇测定相比,总17α-雌二醇测定对诱导排卵的卵泡数有更好的诱导作用。

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J Reprod Dev. 2018 Jun 22;64(3):203-208. doi: 10.1262/jrd.2017-153. Epub 2018 Mar 6.
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GPR30 mediates estrone, estriol, and estradiol to suppress gonadotropin-releasing hormone-induced luteinizing hormone secretion in the anterior pituitary of heifers.GPR30介导雌酮、雌三醇和雌二醇抑制小母牛垂体前叶中促性腺激素释放激素诱导的促黄体生成素分泌。
J Reprod Dev. 2017 Oct 18;63(5):519-525. doi: 10.1262/jrd.2017-035. Epub 2017 Aug 6.
3
Effect of synchronization of follicle-wave emergence with estradiol and progesterone and superstimulation with follicle-stimulating hormone on milk estrogen concentrations in dairy cattle.
卵泡波出现与雌二醇和孕酮同步以及用促卵泡激素进行超刺激对奶牛乳汁雌激素浓度的影响。
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