Saumande J, Lopez-Sebastian A
J Reprod Fertil. 1982 Nov;66(2):411-6. doi: 10.1530/jrf.0.0660411.
Oestradiol-17 beta and conjugated oestrone, oestradiol-17 beta and oestradiol-17 alpha were measured in peripheral plasma of heifers treated with PMSG/PGF-2 alpha to induce superovulation. Changes in the concentrations of each hormone were synchronous, the highest level being near oestrus. For a given number of ovulations the hormone with the highest concentration was total oestradiol-17 alpha, then came total oestrone, total oestradiol-17 beta and oestradiol-17 beta. For each oestrogen, the maximum preovulatory concentration measured was significantly correlated with the number of ovulations; the regression line for total oestradiol-17 alpha was twice as steep as that for oestradiol-17 beta. It is concluded that in animals treated to induce superovulation assay of total oestradiol-17 alpha gives a better induction of the number of follicles induced to ovulate than does the more conventional assay of oestradiol-17 beta.
对用孕马血清促性腺激素/前列腺素F-2α处理以诱导超排卵的小母牛外周血浆中的17β-雌二醇、结合雌酮、17β-雌二醇和17α-雌二醇进行了测定。每种激素浓度的变化是同步的,最高水平接近发情期。对于给定的排卵数,浓度最高的激素是总17α-雌二醇,其次是总雌酮、总17β-雌二醇和17β-雌二醇。对于每种雌激素,测得的排卵前最大浓度与排卵数显著相关;总17α-雌二醇的回归线斜率是17β-雌二醇的两倍。得出的结论是,在经处理诱导超排卵的动物中,与更传统的17β-雌二醇测定相比,总17α-雌二醇测定对诱导排卵的卵泡数有更好的诱导作用。