Francioli P, Vogt M, Schädelin J, Clément F, Russi E, Delacrétaz F, Perret C, Glauser M P
Schweiz Med Wochenschr. 1982 Nov 20;112(47):1682-7.
Three cases of multiple opportunistic infections in previously healthy homosexual males were observed in 3 different University Hospitals in Switzerland. Two of the patients died. Infections were multiple, with P. carinii pneumonia (3 cases), chronic mucocutaneous ulcers probably due to Herpes simplex virus (2 cases), mucosal candidiasis (2 cases) and disseminated infections due to cytomegalovirus (1 case) and Mycobacterium avium (1 case). All patients had depressed cellular immunity with marked lymphopenia. These cases are similar to those recently observed in the United States, but two of the patients had never been to the USA although both had vacationed in Haïti where the syndrome has been described. These patients illustrate that this new syndrome should also be suspected outside the USA when a patient (especially a male homosexual) presents with persistent fever of unknown origin and develops opportunistic infections without obvious underlying disease.
在瑞士的3家不同大学医院观察到3例先前健康的同性恋男性发生多种机会性感染。其中2例患者死亡。感染是多重的,包括卡氏肺孢子虫肺炎(3例)、可能由单纯疱疹病毒引起的慢性黏膜皮肤溃疡(2例)、黏膜念珠菌病(2例)以及由巨细胞病毒(1例)和鸟分枝杆菌(1例)引起的播散性感染。所有患者的细胞免疫功能均低下,伴有明显的淋巴细胞减少。这些病例与最近在美国观察到的病例相似,但其中2例患者从未去过美国,尽管两人都曾在已描述过该综合征的海地度假。这些患者表明,当患者(尤其是男性同性恋者)出现不明原因的持续发热并在无明显基础疾病的情况下发生机会性感染时,在美国以外的地区也应怀疑这种新综合征。