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[获得性免疫缺陷综合征、机会性感染与同性恋。瑞士所研究的3例病例报告]

[Acquired immunologic deficiency syndrome, opportunistic infections and homosexuality. Presentation of 3 cases studied in Switzerland].

作者信息

Francioli P, Vogt M, Schädelin J, Clément F, Russi E, Delacrétaz F, Perret C, Glauser M P

出版信息

Schweiz Med Wochenschr. 1982 Nov 20;112(47):1682-7.

PMID:6294820
Abstract

Three cases of multiple opportunistic infections in previously healthy homosexual males were observed in 3 different University Hospitals in Switzerland. Two of the patients died. Infections were multiple, with P. carinii pneumonia (3 cases), chronic mucocutaneous ulcers probably due to Herpes simplex virus (2 cases), mucosal candidiasis (2 cases) and disseminated infections due to cytomegalovirus (1 case) and Mycobacterium avium (1 case). All patients had depressed cellular immunity with marked lymphopenia. These cases are similar to those recently observed in the United States, but two of the patients had never been to the USA although both had vacationed in Haïti where the syndrome has been described. These patients illustrate that this new syndrome should also be suspected outside the USA when a patient (especially a male homosexual) presents with persistent fever of unknown origin and develops opportunistic infections without obvious underlying disease.

摘要

在瑞士的3家不同大学医院观察到3例先前健康的同性恋男性发生多种机会性感染。其中2例患者死亡。感染是多重的,包括卡氏肺孢子虫肺炎(3例)、可能由单纯疱疹病毒引起的慢性黏膜皮肤溃疡(2例)、黏膜念珠菌病(2例)以及由巨细胞病毒(1例)和鸟分枝杆菌(1例)引起的播散性感染。所有患者的细胞免疫功能均低下,伴有明显的淋巴细胞减少。这些病例与最近在美国观察到的病例相似,但其中2例患者从未去过美国,尽管两人都曾在已描述过该综合征的海地度假。这些患者表明,当患者(尤其是男性同性恋者)出现不明原因的持续发热并在无明显基础疾病的情况下发生机会性感染时,在美国以外的地区也应怀疑这种新综合征。

相似文献

1
[Acquired immunologic deficiency syndrome, opportunistic infections and homosexuality. Presentation of 3 cases studied in Switzerland].[获得性免疫缺陷综合征、机会性感染与同性恋。瑞士所研究的3例病例报告]
Schweiz Med Wochenschr. 1982 Nov 20;112(47):1682-7.
2
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N Engl J Med. 1981 Dec 10;305(24):1425-31. doi: 10.1056/NEJM198112103052401.
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[Acquired immunodeficiency syndrome, Kaposi's disease and cerebral toxoplasmosis in a young man. Review of the literature apropos of a case].[一名年轻男性的获得性免疫缺陷综合征、卡波西肉瘤病和脑弓形虫病。关于一例病例的文献综述]
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Acquired immune deficiency in Haitians: opportunistic infections in previously healthy Haitian immigrants.海地人的获得性免疫缺陷:既往健康的海地移民中的机会性感染。
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AIDS - a new plague?艾滋病——一种新的瘟疫?
Eur J Clin Microbiol. 1983 Jun;2(3):183-5. doi: 10.1007/BF02029512.
2
Clinical and epidemiological survey of acquired immune deficiency syndrome in Europe.欧洲获得性免疫缺陷综合征的临床与流行病学调查。
Eur J Clin Microbiol. 1984 Feb;3(1):55-8. doi: 10.1007/BF02032823.