• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Inhibition of nicotinic acid and nicotinamide uptake into Bordetella pertussis by structural analogues.

作者信息

McPheat W L, Wardlaw A C

出版信息

J Gen Microbiol. 1982 Nov;128(11):2681-5. doi: 10.1099/00221287-128-11-2681.

DOI:10.1099/00221287-128-11-2681
PMID:6296274
Abstract

3-Pyridine-carboxaldehyde and 3-pyridine-aldoxime were effective and specific inhibitors of the uptake of both nicotinic acid (NA) and nicotinamide (ND) by Bordetella pertussis, although neither compound inhibited the growth of the bacteria in liquid medium or the oxidation of glutamate by washed suspensions. In contrast, the following pyridine derivatives did not inhibit uptake of NA or ND: iso-NA, iso-ND, isoniazid, 6-amino-NA and 6-amino-ND, 3-acetyl-pyridine, 3-pyridyl-acetic acid, N,N-diethyl-ND and 3-pyridine-sulphonic acid. 3- Pyridyl-carbinol was inhibitory, but less so than the first listed compounds.

摘要

相似文献

1
Inhibition of nicotinic acid and nicotinamide uptake into Bordetella pertussis by structural analogues.
J Gen Microbiol. 1982 Nov;128(11):2681-5. doi: 10.1099/00221287-128-11-2681.
2
Preliminary evidence for a pyridine nucleotide cycle in Bordetella pertussis.百日咳博德特氏菌中吡啶核苷酸循环的初步证据。
Antonie Van Leeuwenhoek. 1984;50(1):33-7. doi: 10.1007/BF00404905.
3
Modulation of Bordetella pertussis by nicotinic acid.烟酸对百日咳博德特氏菌的调节作用。
Infect Immun. 1983 Aug;41(2):516-22. doi: 10.1128/iai.41.2.516-522.1983.
4
Effect of pyridines on phenotypic properties of Bordetella pertussis.吡啶对百日咳博德特氏菌表型特性的影响。
Infect Immun. 1982 Nov;38(2):548-53. doi: 10.1128/iai.38.2.548-553.1982.
5
Isoniazid perturbation of the pyridine nucleotide cycle of Escherichia coli.异烟肼对大肠杆菌吡啶核苷酸循环的干扰。
Microbios. 1982;35(141-142):169-78.
6
[Nicotinic acid and nicotinamide].[烟酸和烟酰胺]
Nihon Rinsho. 1999 Oct;57(10):2211-7.
7
Metabolic fate of nicotinamide in higher plants.烟酰胺在高等植物中的代谢命运。
Physiol Plant. 2007 Oct;131(2):191-200. doi: 10.1111/j.1399-3054.2007.00959.x.
8
Significance of enzymatically catalyzed exchange reactions in chemotherapy.
Science. 1954 Sep 17;120(3116):437-40. doi: 10.1126/science.120.3116.437.
9
Structural mechanism for regulation of DNA binding of BpsR, a Bordetella regulator of biofilm formation, by 6-hydroxynicotinic acid.BpsR 是鲍特氏菌生物膜形成的调控因子,6-羟基烟酸调控其 DNA 结合的结构机制。
PLoS One. 2019 Nov 7;14(11):e0223387. doi: 10.1371/journal.pone.0223387. eCollection 2019.
10
[The dynamic biosynthesis of nicotinamide coenzymes from nicotinamide and nicotinic acid in rat tissues].[大鼠组织中烟酰胺和烟酸动态生物合成烟酰胺辅酶的研究]
Ukr Biokhim Zh (1978). 1996 Mar-Apr;68(2):29-33.

引用本文的文献

1
Metabolic engineering of Escherichia coli for biosynthesis of β-nicotinamide mononucleotide from nicotinamide.大肠杆菌中β-烟酰胺单核苷酸生物合成的代谢工程:从烟酰胺开始。
Microb Biotechnol. 2021 Nov;14(6):2581-2591. doi: 10.1111/1751-7915.13901. Epub 2021 Jul 26.
2
Comparative genomics and functional analysis of the NiaP family uncover nicotinate transporters from bacteria, plants, and mammals.比较基因组学和 NiaP 家族的功能分析揭示了细菌、植物和哺乳动物中的烟碱酸转运蛋白。
Funct Integr Genomics. 2012 Mar;12(1):25-34. doi: 10.1007/s10142-011-0255-y. Epub 2011 Sep 28.
3
Preliminary evidence for a pyridine nucleotide cycle in Bordetella pertussis.
百日咳博德特氏菌中吡啶核苷酸循环的初步证据。
Antonie Van Leeuwenhoek. 1984;50(1):33-7. doi: 10.1007/BF00404905.
4
Modulation of Bordetella pertussis by nicotinic acid.烟酸对百日咳博德特氏菌的调节作用。
Infect Immun. 1983 Aug;41(2):516-22. doi: 10.1128/iai.41.2.516-522.1983.