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爱泼斯坦-巴尔HR-1病毒粒子DNA甲基化程度非常高。

Epstein-Barr HR-1 virion DNA is very highly methylated.

作者信息

Diala E S, Hoffman R M

出版信息

J Virol. 1983 Jan;45(1):482-3. doi: 10.1128/JVI.45.1.482-483.1983.

DOI:10.1128/JVI.45.1.482-483.1983
PMID:6296457
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC256435/
Abstract

The virion DNA of Epstein-Barr virus strain HR-1 was found to be methylated to a very large extent, approaching 15%. This extent of methylation is in great contrast to other classes of tumor viruses, and it is the highest that we know of in any mammalian system.

摘要

爱泼斯坦-巴尔病毒HR-1株的病毒体DNA被发现高度甲基化，甲基化程度接近15%。这种甲基化程度与其他类别的肿瘤病毒形成了鲜明对比，是我们所知的任何哺乳动物系统中最高的。

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Epstein-Barr HR-1 virion DNA is very highly methylated.爱泼斯坦-巴尔HR-1病毒粒子DNA甲基化程度非常高。
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2
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DNA of Epstein-Barr virus. III. Identification of restriction enzyme fragments that contain DNA sequences which differ among strains of Epstein-Barr virus.爱泼斯坦－巴尔病毒的DNA。III. 含有爱泼斯坦－巴尔病毒不同菌株间存在差异的DNA序列的限制性内切酶片段的鉴定。
J Virol. 1978 Aug;27(2):388-98. doi: 10.1128/JVI.27.2.388-398.1978.

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2
Hypomethylation of host cell DNA synthesized after infection or transformation of cells by herpes simplex virus.单纯疱疹病毒感染或转化细胞后合成的宿主细胞DNA的低甲基化。
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本文引用的文献

1
Hypomethylation of HeLa cell DNA and the absence of 5-methylcytosine in SV40 and adenovirus (type 2) DNA: analysis by HPLC.HeLa细胞DNA的低甲基化以及SV40和腺病毒（2型）DNA中5-甲基胞嘧啶的缺失：高效液相色谱分析
Biochem Biophys Res Commun. 1982 Jul 16;107(1):19-26. doi: 10.1016/0006-291x(82)91663-1.
2
Methylation of the viral genome in an in vitro model of herpes simplex virus latency.单纯疱疹病毒潜伏体外模型中病毒基因组的甲基化
Proc Natl Acad Sci U S A. 1982 Apr;79(7):2207-10. doi: 10.1073/pnas.79.7.2207.
3
DNA methylation in normal and SV40-transformed human fibroblasts.
Biochem Biophys Res Commun. 1981 Oct 30;102(4):1379-84. doi: 10.1016/s0006-291x(81)80164-7.
4
Conservation and progressive methylation of Epstein-Barr viral DNA sequences in transformed cells.转化细胞中爱泼斯坦-巴尔病毒DNA序列的保守性和渐进性甲基化
J Virol. 1981 Apr;38(1):305-16. doi: 10.1128/JVI.38.1.305-316.1981.
5
Enzymatic analysis of 5-methylcytosine content in eukaryotic DNA. Study of intracellular Simian Virus 40 DNA.真核生物DNA中5-甲基胞嘧啶含量的酶促分析。细胞内猿猴病毒40 DNA的研究。
J Biol Chem. 1980 Aug 25;255(16):7544-7.
6
DNA methylation and viral gene expression in adenovirus-transformed and -infected cells.腺病毒转化和感染细胞中的DNA甲基化与病毒基因表达。
Nucleic Acids Res. 1980 Jun 11;8(11):2461-73. doi: 10.1093/nar/8.11.2461.
7
DNA methylation in adenovirus, adenovirus-transformed cells, and host cells.
Proc Natl Acad Sci U S A. 1976 Nov;73(11):3923-7. doi: 10.1073/pnas.73.11.3923.
8
Methylation of viral DNA in vivo and in vitro.病毒DNA在体内和体外的甲基化。
Virology. 1979 Nov;99(1):152-7. doi: 10.1016/0042-6822(79)90046-1.
9
DNA of Epstein-Barr virus. III. Identification of restriction enzyme fragments that contain DNA sequences which differ among strains of Epstein-Barr virus.爱泼斯坦－巴尔病毒的DNA。III. 含有爱泼斯坦－巴尔病毒不同菌株间存在差异的DNA序列的限制性内切酶片段的鉴定。
J Virol. 1978 Aug;27(2):388-98. doi: 10.1128/JVI.27.2.388-398.1978.
10
Studies on the in vivo methylation of replicating herpes simplex virus type 1 DNA.单纯疱疹病毒1型复制型DNA的体内甲基化研究。
Virology. 1977 Oct 15;82(2):265-74. doi: 10.1016/0042-6822(77)90002-2.