Gass J D, Guerry R K, Jack R L, Harris G
Arch Ophthalmol. 1978 Mar;96(3):428-35. doi: 10.1001/archopht.1978.03910050204002.
Choroidal osteomas caused visual symptoms in four healthy young women. A positive 32P test led to enucleation and histopathologic confirmation of the diagnosis in one patient. The characteristic ophthalmoscopic findings in these patients included the following: (1) slightly and irregularly elevated, yellow-white, juxtapapillary, choroidal tumor and well-defined geographic borders; (2) diffuse and mottled depigmentation of the overlying pigment epithelium; and (3) multiple small vascular networks on the tumor surface. A diffuse mottled pattern of hyperfluorescence in the area of the tumor occurred during the early and later stages of angiography. The tumors were ultrasonically dense, and the orbital tissue behind them was rendered silent. The tumors were visible on routine orbital x-ray films and computerized tomograms. The latter study demonstrated the tumors as having the consistency of normal bone.
脉络膜骨瘤在四名健康年轻女性中引起了视觉症状。一名患者经32P试验呈阳性后接受了眼球摘除术，组织病理学检查确诊了诊断。这些患者典型的检眼镜检查结果如下：（1）轻微不规则隆起的黄白色、紧邻视乳头的脉络膜肿瘤，边界清晰呈地图状；（2）上方色素上皮弥漫性斑驳状色素脱失；（3）肿瘤表面有多个小血管网。血管造影早期和后期，肿瘤区域出现弥漫性斑驳状高荧光模式。肿瘤超声检查呈高密度，其后方的眶组织无声。在常规眼眶X线片和计算机断层扫描上可见肿瘤。后者显示肿瘤具有正常骨质的密度。
