Frenckner B, Lännergren K, Söderlund S
Scand J Thorac Cardiovasc Surg. 1982;16(2):201-4. doi: 10.3109/14017438209101811.
Between 1970 and 1979, 14 patients were operated on for pulmonary metastases. In 9 of these the primary tumour was a Wilms' nephroblastoma. Five out of the 14 patients are presently alive and free from disease (3 to 10 years after pulmonary resection). Primary tumours of the survivors were Wilms' tumour in 3 cases, an ovarian teratoma in one patient and a Ewing's sarcoma in one patient. Two of survivors had bilateral involvement and one had multiple metastases of one lung with pleural exudation. The disease-free interval was the same among the survivors and the non-survivors. It is apparent from the present material that some patients with a very poor prognosis as predicted from different prognostic factors can be cured after surgical excision of the metastases. The surgical procedure in children involves a very small risk and only moderate discomfort. An active surgical approach is therefore recommended.
1970年至1979年间,14例患者接受了肺转移瘤手术。其中9例的原发肿瘤为威尔姆斯肾母细胞瘤。14例患者中有5例目前存活且无疾病(肺切除术后3至10年)。存活者的原发肿瘤3例为威尔姆斯瘤,1例为卵巢畸胎瘤,1例为尤因肉瘤。2名存活者双侧受累,1名有一侧肺的多发转移伴胸腔积液。存活者和非存活者的无病间期相同。从目前的资料来看,一些根据不同预后因素预测预后很差的患者,在手术切除转移瘤后可以治愈。儿童的手术操作风险非常小,不适也很轻微。因此建议采取积极的手术方法。