[Furosemide at high doses in a girl with chronic renal failure].

A case is reported of a female preschool, age child with nephrotic syndrome, probably secondary to focal and segmentary hyalinosis with progressive decrease of the renal function. The patient was given increasing doses of furosemide to control the important retention of fluids she showed until a daily dose of 120 mg/kg. of body weight was reached. Adequate control of edema was managed and it was possible to decrease sodium restriction from the diet when urinary excretion of sodium increased. Such effect was useful for four months during which, the patient's diet turned more adequate and there was improvement of the nutritional state which was seriously impaired because of the restrictive diet given. However, control was lost because the patient died at home from bronchopneumonia. Thus, it is considered furosemide may be used in chronic renal failure at higher than usual doses in selected patients.